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Latest Shanghai Stem Cell Institute Stories

2011-12-02 01:50:56

FINDINGS: Tweaking the levels of factors used during the reprogramming of adult cells into induced pluriopotent stem (iPS) cells can greatly affect the quality of the resulting iPS cells, according to Whitehead Institute researchers. This finding explains at least in part the wide variation in quality and fidelity of iPS cells created through different reprogramming methods. RELEVANCE: Like embryonic stem cells, iPS cells can become any cell type in the body, a characteristic that could...

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2011-06-10 05:35:00

According to a new study by researchers at the Stanford University Medical Center, the Mayo Clinic and the University of Michigan, any legislation that slows human embryonic stem cell research is likely to also seriously harm the study of induced pluripotent stem cells. The findings refute the idea that embryonic stem cell research can be abandoned in favor of the less-controversial iPS cells. "If federal funding stops for human embryonic stem cell research, it would have a serious negative...

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2011-02-02 10:41:33

Researchers at Johns Hopkins have found a better way to create induced pluripotent stem (iPS) cells"”adult cells reprogrammed with the properties of embryonic stem cells"”from a small blood sample. This new method, described last week in Cell Research, avoids creating DNA changes that could lead to tumor formation. "These iPS cells are much safer than ones made with previous technologies because they don't involve integrating foreign viruses that can potentially lead to...

2010-07-27 12:36:33

Australian scientists from the Monash Institute of Medical Research have "reprogrammed" adult mouse fat cells and neural cells to become stem cells that can differentiate into a variety of different cells (pluripotency). The cells, called "induced pluripotent stem cells" (iPS), are nearly identical to the naturally occurring pluripotent stems cells, such as embryonic stem cells, which are highly pluripotent, in short supply and their access restricted in the U.S. The study is published in...

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2010-07-02 05:35:00

Stored samples of frozen blood can be used to make cells that resemble stem cells, potentially creating a new and easier source for the valued cells, researchers said on Thursday. The researchers used cells from blood to make induced pluripotent cells (iPS cells) -- cells that closely resemble human embryonic stem cells but are made from ordinary tissue. IPS cells have been made from skin in the past, but blood is much easier to take from people and to store, the researchers reported....

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2010-06-30 06:37:19

TAU develops method for tracking adult stem cells as they regress Cell reprogramming calls The Curious Case of Benjamin Button to mind. It's a new technology that uses molecular therapy to coax adult cells to revert to an embryonic stem cell-like state, allowing scientists to later re-differentiate these cells into specific types with the potential to treat heart attacks or diseases such as Parkinson's. But at this point in the technology's development, only one percent of cells are...

2010-02-08 06:43:07

Provides 'a better inkling of what we might aim for before differentiating iPS cells to clinically useful cell types' In the Feb. 7 issue of the journal Nature, scientists at the Genome Institute of Singapore (GIS), report that a genetic molecule, called Tbx3, which is crucial for many aspects of early developmental processes in mammals, significantly improves the quality of stem cells that have been reprogrammed from differentiated cells. Stem cells reprogrammed from differentiated cells are...

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2009-07-24 06:35:00

Scientists on Thursday announced the creation of mice from reprogrammed induced pluripotent stem cells. Writing in the journal Nature, Dr. Shaorong Gao and colleagues from the National Institute of Biological Sciences in Beijing, China said they used a new technique to make Xiao Xiao, or Tiny, as the first mouse ever created from reprogrammed adult pluripotent cells. "This gives us hope for future therapeutic interventions," said Fanyi Zeng of the Shanghai Institute of Medical Genetic at...

2009-07-07 07:05:19

UCLA researchers have found that embryonic stem cells and skin cells reprogrammed into embryonic-like stem cells have inherent molecular differences, demonstrating for the first time that the two cell types are clearly distinguishable from one another. The data from the study suggest that embryonic stem cells and the reprogrammed cells, known as induced pluripotent stem (iPS) cells, have overlapping but still distinct gene expression signatures. The iPS cells, like embryonic stem cells, have...

2009-04-24 15:15:03

Scientists in California say they've made an important step forward in the race to make reprogrammed stem cells without problematic genes. Shen Ding and colleagues at the Scripps Research Institute say they've developed a way to reprogram mouse cells to form stem cells using a combination of purified proteins and a chemical additive. The finding, published online in the journal Cell Stem Cell, may help researchers get around a major drawback to the use of induced pluripotent stem (iPS) cells...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.