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Latest Shigella Stories

2014-06-27 23:03:36

Moderate to severe diarrhea is a major cause of childhood mortality in developing countries and ranks as one of the top four causes of death among young children in sub-Saharan Africa and South Asia. In a finding that may one day help control this disease, researchers have identified microorganisms not widely linked to the condition previously that may trigger diarrheal disease and others that may protect against it. College Park, MD (PRWEB) June 27, 2014 In a finding that may one day...

2013-05-22 15:28:54

How does the bacterium Shigella–the cause of a deadly diarrheal disease–detect that it's in a human host? Ohio University scientists have found that a biological "RNA thermometer" monitors whether the environment is right for the bacterium to produce the factors it needs to survive within the body, according to a study published May 21 in the journal PLOS ONE. The scientists have been seeking more information about the genetic pathways of Shigella in the hope of finding new...

2013-04-04 15:03:51

UT Southwestern Medical Center researchers report that a pathogen annually blamed for an estimated 90 million cases of food-borne illness defeats a host's immune response by using a fat-snipping enzyme to cut off cellular communication. "Our findings provide insight into severe bacterial infectious diseases, as well as some forms of cancer, in which the attachment of fat molecules to proteins is an essential feature of the disease process," said Dr. Neal Alto, assistant professor of...

2012-08-06 11:16:49

Researchers look at the spread of dysentery from Europe to industrializing countries Researchers have found that a bacterium that emerged centuries ago in Europe has now been spreading globally into countries undergoing rapid development and industrialization. Unlike other diarrheal diseases, this one is unlikely to be resolved by providing access to clean water. As developing countries become more industrialized the numbers of infections with dysentery-causing Shigella flexneri are known...

2012-07-04 23:18:35

A hospital-based surveillance study conducted by Ciara O'Reilly of the Centers for Disease Control and Prevention, Atlanta, Georgia, USA and colleagues describes the risk factors for death amongst children who have been hospitalized with diarrhea in rural Kenya. Reporting in this week's PLoS Medicine, the authors found that infections with nontyphoidal Salmonella and with Shigella (but not with rotavirus) were associated with an increased risk of death. The authors state that: "This...

New Genetic Path To Deadly Diarrheal Disease Discovered
2012-06-12 15:46:42

Scientists have found new genetic information that shows how harmful bacteria cause the acute diarrheal disease shigellosis, which kills more than a million people worldwide each year. The research, which could lead to the development of future treatments, was published today in the journal PLoS ONE. The study was led by Ohio University scientist Erin Murphy and doctoral student William Broach, with contributions from University of Nevada, Las Vegas and University of Texas at Austin...

2012-01-19 18:03:17

Findings could provide basis for first treatment for Shiga toxin infection Carnegie Mellon University researchers have discovered that an element commonly found in nature might provide a way to neutralize the potentially lethal effects of a compound known as Shiga toxin. New results published in the Jan. 20 issue of Science by Carnegie Mellon biologists Adam Linstedt and Somshuvra Mukhopadhyay show that manganese completely protects against Shiga toxicosis in animal models. Produced by...

2011-11-21 10:09:44

New publication demonstrates ability of Avidocin proteins to prevent and treat E. coli O157 diarrhea in animal study A novel antibacterial protein targeted against E. coli O157:H7 may offer a way to prevent or treat serious food-borne bacterial infections, as demonstrated in a study published in the December issue of Antimicrobial Agents and Chemotherapy. Results in an animal model of E. coli infection showed that the orally administered protein, developed by AvidBiotics, Inc., could...


Latest Shigella Reference Libraries

72_04c5b3879bb85672771defa94bb4ac91
2011-04-15 14:54:29

Escherichia coli is a Gram-negative rod-shaped bacterium that is commonly found in the lower intestine of warm-blooded organisms. Most strains are harmless; however, some such as O157:H7 can cause food poisoning in humans and are often responsible for product recalls. The normal flora of the gut normally contains the harmless strains and often provide K2 to the body. They are not always confined to the intestine and have the ability to survive briefly outside of the body. It grows easily...

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Word of the Day
pungle
  • To take pains; labor assiduously with little progress.
This word comes from the Spanish 'pongale,' put it.
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