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Last updated on April 17, 2014 at 1:21 EDT

Latest Sirtuin Stories

2009-08-03 19:20:00

Sirtuin proteins have been shown to promote longevity in many organisms, and increased expression of one sirtuin protein, SIRT3, has been linked to increased human lifespan. New data, generated in mice, by Mahesh Gupta and colleagues, at the University of Chicago, Chicago, has revealed that Sirt3 helps protect the mouse heart.In the study, the heart of mice lacking Sirt3 was found to show signs of becoming enlarged (a process known as cardiac hypertrophy), at about 8 weeks of age. Further,...

2009-07-09 15:08:00

FT. LEE, N.J., July 9 /PRNewswire/ -- Red wine (resveratrol) pills appear to be the rage these days and a local group of cardiologists wants to lead the way for patients and consumers to learn more about them. They may be among the first U.S. cardiologists to do so. (Photo: http://www.newscom.com/cgi-bin/prnh/20090709/LA44390) In response to growing inquiries about the heart-healthy properties of red wine pills, a local cardiology group says it will soon begin to study the effects of these...

2009-06-11 15:42:10

Resveratrol shows therapeutic potential for cancer chemoprevention as well as cardioprotection. Resveratrol may aid in the prevention of age-related disorders, such as neurodegenerative diseases, inflammation, diabetes, and cardiovascular disease. Low doses of resveratrol improve cell survival as a component of cardio- and neuro-protection, while high doses increase cell death.   The benefits of alcohol are all about moderation. Low to moderate drinking "“ especially of red...

2009-06-10 14:31:19

Researchers at The Wistar Institute have defined a key target of an evolutionarily conserved protein that regulates the process of aging. The study, published June 11 in Nature, provides fundamental knowledge about key mechanisms of aging that could point toward new anti-aging strategies and cancer therapies.Scientists have long known that a class of proteins called sirtuins promotes fitness and longevity in most organisms ranging from single-celled yeast to mammals. At the cellular level,...

2009-05-18 23:52:55

U.S. researchers have found cocaine regulated molecular pathways that may lead to addiction treatments. The study, published in Cell Press, finds long-lasting changes in behavior are elicited as cocaine regulates gene expression in a crucial reward region of the brain. Although we have known for some time that changes in gene expression contribute to the long-lasting regulation of the brain's reward circuitry that is seen during drug addiction, how those specific genes are regulated is not...

2009-05-13 15:09:47

New research sheds light on how cocaine regulates gene expression in a crucial reward region of the brain to elicit long-lasting changes in behavior. The study, published by Cell Press in the May 14th issue of the journal Neuron, provides exciting insight into the molecular pathways regulated by cocaine and may lead to new strategies for battling drug addiction. It is well established that addictive drugs induce persistent changes in the brain's reward circuits. Previous research has...

2009-03-10 16:08:00

SAN DIMAS, Calif., March 10 /PRNewswire/ -- A recent CBS 60 Minutes TV program drew considerable attention to resveratrol (rez-vair-ah-trawl), a red wine molecule believed to largely be responsible for the French Paradox, the fact the French have far more people living beyond 100 years and exhibit a far lower mortality rate from heart disease than other people living in other developed countries, despite the high-calorie, high-fat diet in France. (Photo:...

2009-02-27 10:00:00

TORONTO, Feb. 27 /PRNewswire/ -- The following was written by W. Gifford-Jones M.D., a medical journalist. How do the French differ from North Americans? They eat fat-rich, calorie-packed baked goodies which are not heart healthy. Yet they're less likely to die from cardiovascular disease than North Americans. It's called "The French Paradox", believed to be linked to resveratrol, a substance found in red wine. Now, a study shows that a red wine pill provides more health benefits than...

2009-01-25 16:00:00

SAN DIMAS, Calif., Jan. 25 /PRNewswire/ -- A red wine resveratrol (rez-vair-ah-trawl) pill is edging closer to being confirmed as an anti-aging pill as researchers at LifeGen Technologies in Madison, Wisconsin, who were recently interviewed on CBS-TV's 60 MINUTES, reported this past September that Longevinex(R), a patent-applied-for nutriceutical matrix, activates 9-fold more longevity genes than plain resveratrol at a far lower dose than previously reported. (Photo:...

2008-12-27 12:06:00

SAN DIMAS, Calif., Dec. 27 /PRNewswire/ -- According to the latest science, resveratrol pill users are best advised to consume modest doses of resveratrol plus an array of antioxidant molecules as typically provided in 3 to 5 glasses of aged, red wine, rather than resveratrol alone. (Photo: http://www.newscom.com/cgi-bin/prnh/20080603/LATU039 ) The most recent study shows mega-dose resveratrol alone fails to prolong the life of laboratory mice. In fact, mega-doses shortened...