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Latest Skeletal muscle Stories

2009-07-21 19:15:00

Cells rely on tiny molecular motors to deliver cargo, such as mRNA and organelles, within the cell. The critical nature of this transport system is evidenced by the fact that disruption of motors by genetic defects leads to fatal diseases in humans. Although investigators have isolated these motor to study their function in a controlled environment outside the cell, it has been difficult for researchers to follow these fascinating molecular transporters in their natural environment, the...

2009-07-21 13:47:35

A research collaboration between Munich-based biophysicists and a structural biologist in Hamburg is helping to explain why our muscles, and those of other animals, don't simply fall apart under stress. Their findings may have implications for fields as diverse as medical research and nanotechnology.The real strength of any skeletal muscle doesn't start with exercise; it comes ultimately from nanoscale biological building blocks. One key element is a bond involving titin, a giant among...

2009-07-01 09:01:31

Scientists in the UK and Denmark have shown that if elderly men were given growth hormone and exercised their legs showed an appreciable muscle mass increase. Dr. Geoff Goldspink (Royal Free and University College Medical School, UK) says: "This raises the question: Can age-related loss of muscle strength and increased fragility be ameliorated by the therapeutic application of mechano growth factor (MGF)?". There is hope that MGF can also help sufferers of diseases such as muscular dystrophy,...

2009-06-29 16:31:52

Exercise requires the integrated activity of every organ and tissue in the body, and understanding how these respond to the decreased oxygen levels present at moderate to high altitude is the focus of the current special issue of High Altitude Medicine & Biology, a peer-reviewed journal published by Mary Ann Liebert, Inc. (www.liebertpub.com). The entire issue is available free online at www.liebertpub.com/ham Guest Editor Peter D. Wagner, MD, Distinguished Professor of Medicine &...

2009-06-12 07:33:17

New research shows that muscle atrophy is a much more ordered and deliberate process than previously thought. During atrophy, which can occur when the body is weak from a disease such as cancer or AIDS, the body cannibalizes itself and breaks down muscle proteins to liberate amino acids. According to a new study, scientists have learned that a specific enzyme selectively degrades the thick filaments in the muscle but leaves the thin filaments alone. This allows muscles to remain muscles and...

2009-06-11 11:24:44

Researchers have found a potential new treatment for the common problem of muscle atrophy. Results of the animal study were presented at The Endocrine Society's 91st Annual Meeting in Washington, D.C.Muscular atrophy is a debilitating process that results in an extensive loss of muscle mass and function, which greatly worsens quality of life. It occurs in diseases such as cancer, diabetes, AIDS and heart failure, negatively affecting the patients' prognosis. Also, muscular atrophy can occur...

2009-06-10 12:37:53

Two signals "“ an external one from retinoic acid and an internal one from the transcription factor Neurogenin2 "“ cooperate to activate chromatin (the basic material of chromosomes) and help determine that certain nerve progenitor cells become motor neurons, said researchers from Baylor College of Medicine (www.bcm.edu) in a report in the current issue of the journal Neuron."This finding is important for many reasons. For example, as we understand more about what happens, the...

2009-06-08 11:36:41

During desperate times, such as fasting, or muscle wasting that afflicts cancer or AIDS patients, the body cannibalizes itself, atrophying and breaking down skeletal muscle proteins to liberate amino acids. In a new study published online June 8 and in the June 15, 2009 print issue of the Journal of Cell Biology (www.jcb.org), Shenhav Cohen, Alfred Goldberg, and colleagues show that muscle atrophy is a more ordered process than was previously thought. These researchers find evidence that...

2009-06-04 12:14:53

Scientists at the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa have discovered a powerful new way to stimulate muscle regeneration, paving the way for new treatments for debilitating conditions such as muscular dystrophy.The research, to be published in the June 5 issue of Cell Stem Cell, shows for the first time that a protein called Wnt7a increases the number of stem cells in muscle tissue, leading to accelerated growth and repair of skeletal muscle."This discovery...

2009-05-25 09:37:01

New study shows heart muscle protein can replace its missing skeletal muscle counterpart to give mice with myopathy a long and active life A heart muscle protein can replace its missing skeletal muscle counterpart to give mice with myopathy a long and active life, show Nowak et al. The findings will be published online on Monday, May 25, 2009 and will appear in the June 1, 2009 print issue of the Journal of Cell Biology. The contraction machinery protein, actin, exists in different forms in...


Word of the Day
Cthulhu
  • A gigantic fictional humanoid alien god being described with a head resembling an octopus and dragon wings and claws, around whom an insane cult developed.
  • Pertaining to the mythos of Cthulhu and additional otherworldly beings created by H. P. Lovecraft or inspired by his writings and imitators.
This word was invented in 1926 by H.P. Lovecraft for his short story, 'The Call of Cthulhu.' 'Cthulhu' may be based on the word 'chthonic,' which in Greek mythology refers to the underworld.
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