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Latest Small hairpin RNA Stories

2012-06-11 20:07:02

The human immune system has a natural ability to identify and attack tumor cells. Natural killer (NK) cells are innate immune cells that are particularly effective at killing tumor cells due to their ability to secrete cytotoxic enzymes. However, mutations have allowed many types of tumors to develop a resistance to NK-mediated killing through ill-defined mechanisms. Dr. Jerome Ritz and colleagues at the Dana-Farber Cancer Institute in Boston sought to pinpoint some of these mechanisms using...

2011-10-03 15:24:35

In a paper published in the October 2011 issue of Experimental Biology and Medicine, a team of researchers at Columbia University Medical Center led by Stephen Tsang, MD, Ph.D have achieved temporary functional preservation of photoreceptors in a mouse model for retinitis pigmentosa (RP) using novel bipartite gene therapy. RP is a heterogeneous disorder characterized by progressive degeneration of rod photoreceptors (which mediate night vision) causing night blindness and eventually total...

2011-04-27 01:01:00

LONDON, April 27, 2011 /PRNewswire-FirstCall/ -- Silence Therapeutics Plc (AIM: SLN), a leading international RNAi therapeutics company, today announces its results for the year ended 31 December 2010. Analyst Conference Call: There will be a call for analysts today at 14:30 BST / 09:30 ET. The conference call can be accessed by dialling: Europe: +44(0)20-7136-2055 U.S.: +1-212-444-0896 Participant PIN...

2011-02-27 00:01:42

In its continuing support of the DECIPHER Project"”an open access platform for genome-wide RNAi screening and analysis, Cellecta released the 3rd DECIPHER shRNA Expression Library Module which targets an additional 5,000 human genes enabling researchers to now analyze the functionality of over 15,000 human genes for various biological processes with all three human modules. Mountain View, CA (PRWEB) February 25, 2011 Today, Cellecta, Inc. released the 3rd Module of the DECIPHER...

2010-10-21 15:50:00

LAS VEGAS, Oct. 21 /PRNewswire/ -- Altogen Biosystems announced the release of its second generation of in vivo RNAi transfection reagent (http://www.altogen.com/mirna.php) in the company's popular in vivo delivery product line: PEG-Liposome siRNA In Vivo Transfection Kit. This reagent is also compatible for in vivo transfection of other negatively charged molecules - RNA, DNA, and small proteins. The company also offers custom encapsulation of target molecules into PEG-liposome in vivo...

2010-08-11 01:00:00

LONDON, Aug. 11 /PRNewswire/ -- Silence Therapeutics plc (AIM: SLN) ("Silence" or the "Company") announces the issuance of United States patent 7,772,203, titled "Methods and Compositions for Controlling Efficacy of RNA Silencing," by the United States Patent and Trademark Office (USPTO). The issued patent generally claims methods of enhancing RNA silencing with a double stranded RNA interference (RNAi) agent. The patent's RNA silencing method claims include coverage for the administering...

2010-06-09 01:00:00

LONDON, June 9 /PRNewswire/ -- Silence Therapeutics plc (AIM: SLN) ("Silence" or the "Company") announces the issuance of United States patent 7,732,593, titled Methods and Compositions For Controlling Efficacy of RNA Silencing, by the United States Patent and Trademark Office (USPTO). The issued patent, which is based on the seminal research of Phillip D. Zamore, Ph.D., Howard Hughes Medical Institute Investigator, the Gretchen Stone Cook Chair of Biomedical Sciences, and Professor of...

2010-05-20 17:29:00

AMSTERDAM, May 20, 2010 /PRNewswire-FirstCall/ -- - Gene Therapy Vector Successfully Delivers shRNA Into Liver Cells Amsterdam Molecular Therapeutics (Euronext: AMT) a world leader in gene therapy, today reported positive preclinical data from a study using an AAV gene therapy product to lower cholesterol. The data show that a single dose of the gene therapy carrying a short hairpin RNA to silence Apolipoprotein B100 (ApoB100), resulted in a reduction of serum cholesterol of...


Word of the Day
grass-comber
  • A landsman who is making his first voyage at sea; a novice who enters naval service from rural life.
According to the OED, a grass-comber is also 'a sailor's term for one who has been a farm-labourer.'