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Latest Small molecule Stories

2014-01-20 09:42:42

A new class of molecules called acyldepsipeptides — ADEPs — may provide a new way to attack bacteria that have developed resistance to antibiotics. Researchers at Brown and MIT have discovered a way to increase the potency of ADEPs by up to 1,200 times. Their findings appear in the Journal of the American Chemical Society. As concerns about bacterial resistance to antibiotics grow, researchers are racing to find new kinds of drugs to replace ones that are no longer effective. One...

2013-09-09 20:33:58

The vision for a new branch of medicine, inspired by the ancient field that began with peg legs and hand hooks, commanded the spotlight in a major address by its pioneer here today at the 246th National Meeting & Exposition of the American Chemical Society (ACS), the world's largest scientific society. Martin D. Burke, M.D., Ph.D., focused on the field he has named "molecular prosthetics," after the small molecules that make up the ingredients in most drugs and the branch of medicine...

Small Molecule Might Play Big Role In Alzheimer's Disease
2012-07-10 10:58:00

Simulations by UC Santa Barbara researchers improve understanding of plaque formation and suggest new diagnostic and treatment options Alzheimer's disease is one of the most dreaded and debilitating illnesses one can develop. Currently, the disease afflicts 6.5 million Americans and the Alzheimer's Association projects it to increase to between 11 and 16 million, or 1 in 85 people, by 2050. Cell death in the brain causes one to grow forgetful, confused and, eventually, catatonic....

2012-06-12 10:38:23

A small molecule developed at the Weizmann Institute prevents a cancer-causing message from entering the cell nucleus What´s good news in one setting might spell disaster in another. In cancer for instance, when a certain cell is commanded to grow and divide without restraint, it´s a welcome message for the cell itself but a tragedy for the person who harbors this cell in his or her body. Weizmann Institute scientists have managed to decipher and block one type of molecular...

Undiscovered Drugs In The Novemdecillions
2012-06-07 05:55:06

Connie K. Ho for redOrbit.com Novemdecillion — now that´s a huge number. A report published in the American Chemical Society journal Chemical Neuroscience estimates that scientists have barely synthesized one tenth of one percent of the possible medicines that could be made. The estimate of these “small molecules” is potentially 1 novemdecillion, which equals a one with 60 zeros or 1 million billion billion billion billion billion billion. The American Chemical...

2012-03-09 02:30:20

Glowing 'Spinach' produces a snapshot of abnormal molecules inside diseased cells, providing clues about how to treat disorders By engineering cells to express a modified RNA called "Spinach," researchers have imaged small-molecule metabolites in living cells and observed how their levels change over time. Metabolites are the products of individual cell metabolism. The ability to measure their rate of production could be used to recognize a cell gone metabolically awry, as in cancer, or...


Word of the Day
drawcansir
  • A blustering, bullying fellow; a pot-valiant braggart; a bully.
This word is named for Draw-Can-Sir, a character in George Villiers' 17th century play The Rehearsal.
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