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Latest Sodium channel Stories

2011-04-28 00:20:02

Fables have long cast scorpions as bad-natured killers of hapless turtles that naively agree to ferry them across rivers. Michigan State University scientists, however, see them in a different light. Ke Dong, MSU insect toxicologist and neurobiologist, studied the effects of scorpion venom with the hopes of finding new ways to protect plants from bugs. The results, which are published in the current issue of the Journal of Biological Chemistry, have revealed new ways in which the venom...

2010-10-26 02:50:03

Scientists are closer to solving one of the many mysteries of multiple sclerosis and other demyelinating diseases, thanks to a recent study conducted at the Salk Institute for Biological Studies. The research revealed a previously unknown connection between two ion channels, which, when misaligned, can cause the many bizarre symptoms that characterize the condition. The findings, reported in this week's online edition of the Proceedings of the National Academy of Sciences (PNAS), provide...

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2010-09-29 09:25:34

New drug treatment triggers sodium ions to regrow nerves and muscle; could extend treatment window for acute injuries Sodium gets a bad rap for contributing to hypertension and cardiovascular disease. Now biologists at Tufts University's School of Arts and Sciences have discovered that sodium also plays a key role in initiating a regenerative response after severe injury. The Tufts scientists have found a way to regenerate injured spinal cord and muscle by using small molecule drugs to...

2009-12-28 21:04:45

Inherited mutations in voltage-gated sodium channels (Navs) are associated with many different human diseases, including genetic forms of epilepsy and chronic pain. Theodore Cummins and colleagues, at Indiana University School of Medicine, Indianapolis, have now determined the functional consequence of three such mutations. As noted by Stephen Cannon and Bruce Bean, in an accompanying commentary, these results suggest that there might be a common mechanism for many channelopathies, diseases...

2009-10-26 14:26:00

NEW YORK, Oct. 26 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue. Reportlinker Adds Ion Channel Modulator Pipelines: Targets and Agents in Development http://www.reportlinker.com/p0156556/Reportlinker-Adds-Ion-Channel-Modulator-Pipelines-Targets-and-Agents-in-Development.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=prnewswire Ion channels represent a significant opportunity to address an underexploited class of...

2009-09-29 12:41:35

Just as people plug in to computers, smart phones and electric outlets to communicate, electric fish communicate by quickly plugging special channels into their cells to generate electrical impulses, University of Texas at Austin researchers have discovered. The fish generate electric fields to navigate, fight and attract mates in murky streams and rivers throughout Central and South America. They do so at night, while trying to avoid predators such as catfish that sense the electric fields....

2009-09-16 13:53:58

Sodium channel gene linked to Dravet syndrome University of Utah medical researchers have identified a gene with mutations that cause febrile seizures and contribute to a severe form of epilepsy known as Dravet syndrome in some of the most vulnerable patients "“ infants 6 months and younger. The discovery, published online in PLoS Genetics, means some infants with Dravet syndrome, a type of epilepsy that often begins with fever-induced (febrile) seizures, would benefit from genetic...

2009-04-28 10:21:54

New JGP study advances conclusions about the Shaker Kv channelThe May 2009 issue of the Journal of General Physiology features an article and accompanying commentary on new experimental evidence that advances previous conclusions about the essential features of the Shaker K+ channel, a voltage-gated potassium (Kv) channel.As Richard Horn (Department of Molecular Physiology and Biophysics, Institute of Hyperexcitability, Jefferson Medical College) explains in his JGP commentary:"Many of the...

2009-01-22 09:00:00

Improvement in brain electrical signaling is critical both for vertebrate evolution and for preventing epileptic seizuresStudies at the University of Pennsylvania School of Medicine on brain electrical signaling offer a fresh perspective on vertebrate evolution, provide additional evidence supporting Darwinian views of evolution, and may also lead to more effective treatment of epileptic seizures in infants. Researchers discovered how evolutionary changes produced a series of improvements in...

2005-07-13 15:25:00

New Haven, Conn. - Yale School of Medicine researchers report the first demonstration that a single mutation in a human sodium channel gene can trigger pain in people with an inherited pain syndrome known as primary erythromelalgia, according to a study published this month in the journal Brain. The research provides novel insights into the molecular basis for altered firing of pain signaling neurons in primary erythromelalgia, according to Stephen Waxman, M.D., senior author of the study,...


Word of the Day
drawcansir
  • A blustering, bullying fellow; a pot-valiant braggart; a bully.
This word is named for Draw-Can-Sir, a character in George Villiers' 17th century play The Rehearsal.
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