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Latest Solid-state nuclear magnetic resonance Stories

2014-01-28 23:21:40

Avomeen Analytical Services partners with university labs to harness specialized instrumentation for investigative chemical analysis. Ann Arbor, MI (PRWEB) January 28, 2014 Avomeen Analytical Services serves manufacturers, pharmaceutical companies, lawyers, and other laboratories with exceptional analytical services in order to formulate new products, investigate product failures, and solve a host of other tough problems. In addition to Avomeen’s state-of-the-art in-house instruments...

2012-03-19 16:05:01

A new method to reveal the structure of proteins could help researchers understand biological molecules — both those involved in causing disease and those performing critical functions in healthy cells.   For roughly a decade, a technique called solid state nuclear magnetic resonance (NMR) spectroscopy has allowed researchers to detect the arrangements of atoms in proteins that defy study by traditional laboratory tools such as X-ray crystallography. But translating solid state...

2012-03-07 20:29:21

Scientists at the University of Warwick have used state-of-the-art nuclear magnetic resonance (NMR) techniques to shed new light on how pharmaceutical molecules pack together in the solid state. Researchers made use of the UK's largest solid-state NMR magnets, housed at the University of Warwick, to carry out the study in collaboration with Astra Zeneca and GlaxoSmithKline. The analytical methods look directly at the hydrogen and nitrogen atoms that are at the heart of so-called...

2010-11-30 16:56:38

Nuclear magnetic resonance (NMR) is one of the best tools for gaining insight into the structure and dynamics of molecules because nuclei in atoms within molecules will behave differently in a variety of chemical environments. Nuclei can be thought of as tiny compasses that align when placed in the field of a strong magnet. Similar to magnetic resonance imaging (MRI), conventional NMR uses short pulses of radio waves to drive nuclei away from equilibrium and a 'signal' emerges as nuclei...

2009-02-10 08:55:57

Solid-state nuclear magnetic resonance, or SSNMR, is a valuable tool to image and analyze the chemical makeup of proteins and other biomolecules. But the imaging process is time-consuming and requires large amounts of costly isotope-labeled sample for study.Yoshitaka Ishii, associate professor of chemistry at the University of Illinois at Chicago, believes he has found a quicker and more efficient approach to using SSNMR called paramagnetic relaxation-assisted condensed data collection, or...

2008-05-16 06:00:00

By Lawrie, Kirsten J Meredith, Paul; McGeary, Ross P ABSTRACT The isolation, structure determination and chemical characterization of eumelanins has been plagued by their very low solubility in organic solvents. To gain insights into the structure and reactivity of these unusual and important biologic macromolecules and to pave the way for their use in electronics, we have prepared soluble melanins via the synthesis of monomeric precursors containing lipophilic substituents. Two such...

2005-11-22 16:29:54

Using a nuclear magnetic resonance technique, University of Illinois at Chicago chemists have obtained the first molecular-level images of precursors of bundled fibrils that form the brain plaques seen in Alzheimer's disease. Untangling the molecular structure of these pre-fibril forms, which may be the key neurotoxins in Alzheimer's, may help identify targets for new drugs to combat many neurodegenerative diseases. Microscopic bundled fibrils made of proteins called amyloid-beta are...


Word of the Day
omphalos
  • The navel or umbilicus.
  • In Greek archaeology: A central boss, as on a shield, a bowl, etc.
  • A sacred stone in the temple of Apollo at Delphi, believed by the Greeks to mark the 'navel' or exact center-point of the earth.
'Omphalos' comes from the ancient Greek.
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