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Last updated on April 17, 2014 at 1:21 EDT

Latest Spanish National Cancer Research Centre Stories

2014-04-04 12:23:54

These genes could explain why some women with high-risk mutations suffer from cancer while others do not Today we know that women carrying BCRA1 and BCRA2 gene mutations have a 43% to 88% risk of developing from breast cancer before the age of 70. Taking critical decisions such as opting for preventive surgery when the risk bracket is so wide is not easy. Spanish National Cancer Research Centre (CNIO) researchers are conducting a study that will contribute towards giving every woman far...

2013-12-18 12:25:31

DARMSTADT, Germany, December 18, 2013 /PRNewswire/ -- - New agreement aims to translate CNIO research into new potential treatment options for cancer patients - License agreement encompasses two series of ATR inhibitors and a screening platform Merck Serono, the biopharmaceutical division of Merck, today announced that a license agreement has been signed with the Spanish National Cancer Research Centre (CNIO) in Madrid in the...

2013-11-20 17:37:34

PrimPol allows cells to make copies of their DNA even when it is damaged, and prevents breaks in the chromosomes Every day, the human body produces new cells to regenerate tissues and repair those that have suffered injury. Each time this happens, the cells make copies of their DNA that they will pass on to the resulting daughter cells. This process of copying the DNA, also called replication, is very delicate, given that it can generate severe alterations in the DNA that are associated...

2013-11-19 13:16:54

An original model that would explain how regions of the genome that are copied later on facilitate the birth of new genes with specific functions in tissues and organs One of the most important processes in the life of cells is genome replication, which consists of making exact copies of the DNA in order to pass it on to their offspring when they split. In most organisms, from yeast to human beings, genome replication follows a set plan, in which certain regions of the genome replicate...

2013-10-08 13:26:58

A study led by Marcos Malumbres, head of CNIO's Cell Division & Cancer Group, identifies a new molecular mechanism that regulates genome stability and cell proliferation Cell division is an essential process for the development of an organism. This process, however, can cause tumor growth when it stops working properly. Tumor cells accumulate alterations in their genetic material, and this makes them divide in an uncontrolled fashion, thus encouraging growth of the tumor. Over the past...

2013-07-19 23:20:39

In a study, a gene was found to be the key role in obesity. Prescopodene Nutritionals feels they have a way to combat genetics with a diet supplement to help control weight. Washington, USA (PRWEB) July 19, 2013 In an article found on Sciencedaily.com, researchers from the Spanish National Cancer Research Centre (CNIO) discovered the key role of the gene RAP1, a gene that protects telomeres – the ends of chromosomes – and it’s link to obesity. "We still don't know what...

2013-06-21 10:49:14

RAP1 is a gene that also protects telomeres. This is the first time that a link has been found between these structures that shorten with ageing and obesity The discovery of an unexpected function for a gene that was associated to another process in the organism might be a solution in search of a problem, a clue to unsuspected connections. That is what has happened with RAP1, a gene that protects telomeres— the ends of chromosomes—after researchers from the Spanish National Cancer...

Evolutionary History Of Cancer-related Gene Tracked By CNIO Study
2013-06-06 20:59:35

Centro Nacional de Investigaciones Oncologicas (CNIO) The study reveals how a genetic duplication that occurred millions of years ago encouraged the evolution of the ASF1b gene, involved in cancer development How and when evolution generates diversity or gives form to proteins, living beings' functional building blocks, are essential questions that still surround the theory of evolution. In humans, the majority of genes have emerged via genetic duplication, a strategy in which a gene...

2013-04-25 20:16:17

A study led by Oscar Fernandez-Capetillo has deciphered the components of the machinery that duplicates DNA, the replisome, on which most chemotherapeutic agents currently act The Genomic Instability Group led by researcher Óscar Fernández-Capetillo at the Spanish National Cancer Research Centre (CNIO), has for the first time obtained a panoramic photo of the proteins that take part in human DNA division, a process known as replication. The research article,...

2012-09-14 14:31:55

A research project led by CNIO scientists clarifies how tissues and organs select the 'best' cells for themselves, at the expense of 'losers' who might cause disease Scientists from the Spanish National Cancer Research Centre (CNIO) describe how natural selection also occurs at the cellular level, and how our body's tissues and organs strive to retain the best cells in their ranks in order to fend off disease processes. These results appear this week in the new issue of Cell Reports. The...