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Latest Spindle apparatus Stories

9ef6118a4d9055f6ef94e106114bf03d1
2009-02-09 07:23:24

The last step of the cell cycle is the brief but spectacularly dynamic and complicated mitosis phase, which leads to the duplication of one mother cell into two daughter cells. In mitosis, the chromosomes condense and the nucleus breaks down. Fibrous structures called spindles form, which then move the chromosomal material toward opposite ends of a cell and help partition other cell contents. If something goes wrong, diseases such as cancer can arise. Scientists have tried for years to...

2009-02-06 10:03:50

Team finds that Orc1, part of machinery that initiates DNA replication, prevents excess centrosome duplication Before a cell can divide into two, first it must duplicate its genetic material--the DNA packed in its chromosomes. The two new sets of chromosomes then have to be separated from one another and correctly distributed to the resulting "daughter" cells, so that both daughter cells are genetically identical to the original, or "parent," cell. During cell division, a cellular organ...

2009-01-16 13:42:30

Dartmouth Medical School researchers have found two proteins that work in concert to ensure proper chromosome segregation during cell division. Their study is in the January 2009 issue of the journal Nature Cell Biology.This finding is relevant for treating solid cancerous tumors that lose the ability to accurately segregate their chromosomes. Tumors that shuffle chromosomes, a process called chromosomal instability, are known to have a poor prognosis."We show that the function of two...

2009-01-09 12:04:51

A group of Dartmouth researchers has found a new function for one of the proteins involved with chromosome segregation during cell division. Their finding adds to the growing knowledge about the fundamental workings of cells, and contributes to understanding how cell function can go wrong, as it does with cancerous cells.The researchers studied a protein called NOD, distantly related to the motor proteins that power diverse cellular activities, including intracellular transport, signaling,...

2008-12-23 15:05:00

- GlaxoSmithKline continues to lead development activities for GSK-923295 LONDON, Dec. 23 /PRNewswire-FirstCall/ -- GlaxoSmithKline (GSK) and Cytokinetics, Incorporated (Nasdaq: CYTK) announced today that GSK has informed Cytokinetics that it will not exercise its option to license ispinesib or SB-743921 as provided under the Collaboration and License Agreement entered into by the companies in 2001. All rights to ispinesib and SB-743921, each novel inhibitors of kinesin spindle protein...

2446c344a6b20f62a5eafb9921c024851
2006-04-17 15:50:00

SANTA CRUZ, CA-- Scientists have long known that the social insects in the order Hymenoptera--which includes ants, bees, and wasps--have an unusual mechanism for sex determination: Unfertilized eggs develop into males, while fertilized eggs become females. But the development of an unfertilized egg into an adult (called parthenogenesis) remains a mysterious process. One mystery has been the origin of the centrosome, an essential cellular component that is ordinarily derived from the sperm...

2005-11-22 16:08:05

One of the key controllers of neural development seems to depend on a simple cellular decision--whether to divide perpendicularly or in parallel to the embryonic structure called the neuroepithelium. Nevertheless, such orientation is critical, and understanding its machinery could help neuroscientists learn to control the division of adult neural stem cells to regenerate neural tissues. Researchers know that during the earliest embryonic brain development, neural stem cells divide...


Latest Spindle apparatus Reference Libraries

Arbacia punctulata
2013-11-06 11:08:03

Arbacia punctulata is a species of Arbacia genus of purple-spined sea urchins. Its natural habitat is in the Western Atlantic Ocean. It can be found in shallow water from Massachusetts to Cuba and the Yucatan Peninsula, from Texas to Florida in the Gulf of Mexico, the coast from Panama to French Guiana and in the Lesser Antilles, normally on sandy, rocky, or shelly bottoms. It is omnivorous, consuming a wide variety of preys. It’s been shown that it is galactolipids, rather than...

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Word of the Day
monteith
  • A large punch-bowl of the eighteenth century, usually of silver and with a movable rim, and decorated with flutings and a scalloped edge. It was also used for cooling and carrying wine-glasses.
  • A kind of cotton handkerchief having white spots on a colored ground, the spots being produced by a chemical which discharges the color.
This word is possibly named after Monteith (Monteigh), 'an eccentric 17th-century Scotsman who wore a cloak scalloped at the hem.'
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