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Last updated on April 16, 2014 at 14:11 EDT

Latest Spindle checkpoint Stories

2014-02-04 11:35:43

New insights into how the cells in our bodies divide could improve our knowledge of a condition linked to cancer, a study suggests. Errors in the cell division process – which allows us to grow and stay healthy – can lead to a genetic disorder called aneuploidy, which is also associated with birth defects and infertility. Researchers at the University of Edinburgh have pinpointed the key role played by a protein in ensuring that cells separate correctly. During cell division,...

2013-12-11 12:23:42

Researchers at the Cell Cycle Research Group of the Bellvitge Institute of Biomedical Research (IDIBELL) led by Ethel Queralt have reported in the journal PLoS Genetics an article which delve into the regulator mechanisms of mitosis, a key stage of the cell-cycle for the correct transmission of genetic information from parents to sons. Cell-cycle Cells in all organisms grow and divide into two daughter cells by an ordered sequence of events called "cell cycle". Basically, the cells have...

2013-11-29 00:20:06

Tokyo, Nov 29, 2013 - (ACN Newswire) - Researchers at Waseda University in Japan have identified key information to help explain the formation of the "spindle apparatus", a structure required for cell division. Their findings shed light on the mechanisms behind "self-organization" - an essential characteristic of biological structures.Organisms are composed of a variety of structures including muscles, internal organs, and brains, all of which are created through a process known as...

2013-11-25 04:20:04

Tokyo, Nov 25, 2013 - (ACN Newswire) - Researchers at Waseda University in Japan have for the first time directly observed the "molecular motor", called Xkid, that plays a critical role in facilitating the proper alignment of chromosomes during cell division. Their findings are expected to contribute greatly to elucidating the molecular mechanisms of chromosome segregation, a key aspect of the development of certain medical disorders including cancer and birth defects.A human being begins as...

2013-09-12 11:36:20

In a study to be published in the journal Nature, two Dartmouth researchers have found that the protein cyclin A plays an important but previously unknown role in the cell division process, acting as a master controller to ensure the faithful segregation of chromosomes during cell division. Cell division is the process in which cells reproduce by splitting into two identical copies. This process happens trillions of times in an average person's lifetime. To generate two identical copies,...

2011-11-29 07:12:00

IRVINE, Calif., Nov. 29, 2011 /PRNewswire/ -- GeneTex, a leading manufacturer of antibodies and antibody-related reagents, is pleased to announce that they will be launching a new line of antibodies against Hice1 and Hec1. Both of these targets are key players in spindle assembly. (Photo: http://photos.prnewswire.com/prnh/20111129/LA13485-a) (Logo: http://photos.prnewswire.com/prnh/20111129/LA13485LOGO-b) Hice1 is a novel microtubule-associated protein that is required for the...

2010-09-09 10:51:51

University of Pennsylvania biologists studying human reproduction have identified what is likely the major contributing factor to the maternal age-associated increase in aneuploidy, the term for an abnormal number of chromosomes during reproductive cell division. Using naturally aging mouse models, researchers showed that this basic fact of reproductive life is most likely caused by weakened chromosome cohesion.  Older oocytes, or egg cells, have dramatically reduced amounts of a...