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Latest Splice site mutation Stories

2011-06-14 01:16:57

Many more hereditary diseases than previously thought may be caused, at least in part, by errors in pre-mRNA splicing, according to a computer analysis by Brown University scientists. That could be good news because research suggests it may be possible to fix bad splicing. A new Brown University computer analysis that predicts the effect of genetic mutations on how the body splices mRNA indicates as many as a third of disease-related mutations may be linked to splicing problems "” more...