Latest Spliceosome Stories
There are always exceptions to a rule, even one that has prevailed for more than three decades, as demonstrated by a Cold Spring Harbor Laboratory (CSHL) study on RNA splicing, a cellular editing process.
Over the past decade, research in the field of epigenetics has revealed that chemically modified bases are abundant components of the human genome and has forced us to abandon the notion we've had since high school genetics that DNA consists of only four bases.
Because a function of RNA is to be translated as the genetic instructions for the protein-making machinery of cells, RNA editing is the body's way of fine-tuning the proteins it produces, allowing us to adapt.
An international team led by the University of Melbourne Australia, has found that increasing a specific protein in muscles could help treat Duchenne muscular dystrophy (DMD), a severe and progressive muscle wasting disease that affects young boys.
Cardiomyopathy comprises a deterioration of the heart muscle that affects the organ's ability to efficiently pump blood through the body.