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Latest Spliceosome Stories

2012-03-26 11:03:13

Few molecules are more interesting than DNA–except of course RNA. After two decades of research, that "other macromolecule" is no longer considered a mere messenger between glamorous DNA and protein-synthesizing machines. We now know that RNA has been leading a secret life, regulating gene expression and partnering with proteins to form catalytic ribonucleoprotein (RNP) complexes. One of those RNPs is telomerase, an enzyme that maintains chromosome integrity. In the March 25, 2012,...

2012-03-19 19:21:57

Investigators at Nationwide Children's Hospital, working with the DNA Sequencing Core Facility at the University of Utah, have developed an approach to newborn screening (NBS) for the life-threatening genetic disorder, Duchenne muscular dystrophy (DMD) and potentially other muscular dystrophies. As a model for NBS, the approach published online in January in the Annals of Neurology provides evidence that this approach could be implemented if approved by regulatory bodies at a state level or...

2012-03-02 13:00:00

Media integration and events community kicks off voting for awards contest representing the top influencers in the SMB channel. Redmond, WA (PRWEB) March 02, 2012 SMB Nation announced today at its MVP Nation event, that it has officially opened voting for its SMB 150, representing the top 150 influencers in the SMB channel. In addition, for the first time, the media integration and events community, in conjunction with SMB Technology Network (SMBTN), will be holding a live Gala Event on May...

2012-02-16 18:17:54

Understanding how RNA binding proteins control the genetic splicing code is fundamental to human biology and disease — much like editing film can change a movie scene. Abnormal variations in splicing are often implicated in cancer and genetic neurodegenerative disorders. In a step toward deciphering the "splicing code" of the human genome, researchers at the University of California, San Diego School of Medicine have comprehensively analyzed six of the more highly expressed RNA...

2012-01-19 14:55:49

Mutation in 1 copy of U2 snRNA lead to movement problems and early neuron death in mice A Jackson Laboratory research team led by Professor and Howard Hughes Medical Investigator Susan Ackerman, Ph.D., has discovered a defect in the RNA splicing process in neurons that may contribute to neurological disease. The researchers found that a mutation in just one of the many copies of a gene known as U2 snRNAs, which is involved in the intricate processing of protein-encoding RNAs, causes...


Word of the Day
baudekin
  • A rich embroidered or brocaded silk fabric woven originally with a warp of gold thread.
'Baudekin' seems to be an alternative form of 'baldachin,' from the Italian 'Baldacco,' Baghdad, the city where the material was made.
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