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Latest Spliceosome Stories

2011-08-15 18:28:00

View: MDA-AVI BioPharma-YouTube for Mon. 8-15-11 (http://www.youtube.com/watch?v=4pR4a24MHvk ) View: MDA-AVI BioPharma-YouTube for Tues. 8-16-11 (http://www.youtube.com/watch?v=S3aaBZ0az4E) View: MDA-AVI BioPharma-High Res. for Mon. 8-15-11 View: MDA-AVI BioPharma-High Res. for Tues. 8-16-11 TUCSON, Ariz., Aug. 15, 2011 /PRNewswire-USNewswire/ -- More than a decade of targeted Muscular Dystrophy Association-funded research, made possible as a result of generous public support of the...

2011-08-02 07:02:40

(Ivanhoe Newswire) -- The ability to tag proteins with a green fluorescent light to watch how they behave inside cells so revolutionized the understanding of protein biology that it earned the scientific teams who developed the technique Nobel Prizes in 2008. Now, researchers at Weill Cornell Medical College have developed a similar fluorescent tool that can track the mysterious workings of the various forms of cellular RNA. "These fluorescent RNAs offer us a tool that will be critical for...

2011-07-26 06:16:00

LONDON, July 26, 2011 /PRNewswire/ -- Great Ormond Street Hospital has announced that a team led by scientists at its research partner, UCL Institute of Child Health (ICH), funded by the Medical Research Council (MRC) and AVI BioPharma, have made an important breakthrough in the development of a treatment for Duchenne Muscular Dystrophy (DMD). Together with the MDEX Consortium, chaired by the ICH's Professor Francesco Muntoni, the group showed that a gene based drug...

2011-07-14 15:05:40

How the protein U2AF builds mRNA for protein production Scientists at the Technical University of Munich and the Helmholtz Zentrum Muenchen and along with their colleagues from the European Molecular Biology Laboratory (EMBL) in Heidelberg and the Centre for Genomic Regulation in Barcelona have discovered how the U2AF protein enables the pre-mRNA* to be spliced to form the mRNA*, which serves as a template for protein synthesis in the body. Splicing requires the cooperation of different...

2011-06-29 11:20:00

Conference Includes Keynote Speaker and Acclaimed Author Seth Mnookin HACKENSACK, N.J., June 29, 2011 /PRNewswire-USNewswire/ -- Patricia A. Furlong, Founding President and CEO of Parent Project Muscular Dystrophy (PPMD), the largest non-profit organization in the United States focused on finding a cure for Duchenne muscular dystrophy (Duchenne), announced that the Mayor of Baltimore, Maryland, Stephanie Rawlings-Blake, has proclaimed July 8, 2011, to be "End Duchenne Day" in recognition...

2011-06-14 01:16:57

Many more hereditary diseases than previously thought may be caused, at least in part, by errors in pre-mRNA splicing, according to a computer analysis by Brown University scientists. That could be good news because research suggests it may be possible to fix bad splicing. A new Brown University computer analysis that predicts the effect of genetic mutations on how the body splices mRNA indicates as many as a third of disease-related mutations may be linked to splicing problems "” more...

2011-04-20 15:05:19

Intracellular transport mechanism dissected In a multicellular organism, different cells fulfill a range of diversified functions. Often such specialization depends on the delivery of molecular goods to distinct places within a cell. It ensures that particular functions only occur at defined cellular sites. This establishment of intracellular asymmetry in the otherwise fluid environment of the cell cytoplasm requires active transport processes. Messenger RNAs (mRNA) represent an especially...

2011-04-18 17:37:56

Amish population in Ohio has large numbers of MOPD1 Researchers have identified a genetic mutation found in the Ohio Amish population as the cause of a fatal developmental disease in fetuses and infants, according to research published in the April 8, 2011, issue of Science. The genetic mutation is caused by a defect during the cellular protein-making process, causing microcephalic osteodysplastic primoridal dwarfism type 1 (MOPD1), a rare developmental disorder that greatly slows fetal...

2011-04-18 15:08:57

Researchers have long questioned why patients with Duchenne muscular dystrophy (DMD) tend to manage well through childhood and adolescence, yet succumb to their disease in early adulthood, or why elderly people who lose muscle strength following bed rest find it difficult or impossible to regain. Now, researchers at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), part of the National Institutes of Health, are beginning to find answers in a specialized...

2011-04-07 22:12:14

Fetuses with defects in a molecular machine that edits information cells use to make proteins can develop a rare form of dwarfism, according to a new study led by researchers at the Ohio State University Comprehensive Cancer Center "“ Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC "“ James). The defect, triggered by a tiny gene mutation, causes microcephalic osteodysplastic primoridal dwarfism type 1 (MOPD1), a rare developmental disorder that...


Word of the Day
bodacious
  • Remarkable; prodigious.
  • Audacious; gutsy.
  • Completely; extremely.
  • Audaciously; boldly.
  • Impressively great in size; enormous; extraordinary.
This word is probably from the dialectal 'boldacious,' a blend of 'bold' and 'audacious.'
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