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Latest Spliceosome Stories

2010-11-18 16:32:57

Implications for brain diseases such as epilepsy, according to Penn study Cells have their own version of the cut-and-paste editing function called splicing. Researchers at the University of Pennsylvania School of Medicine have documented a novel form of splicing in the cytoplasm of a nerve cell, which dictates a special form of a potassium channel protein in the outer membrane. The channel protein is found in the dendrites of hippocampus cells -- the seat of memory, learning, and spatial...

2010-11-10 11:00:00

HACKENSACK, N.J., Nov. 10, 2010 /PRNewswire-USNewswire/ -- Parent Project Muscular Dystrophy (PPMD), the largest non-profit organization in the United States focused on finding a cure for Duchenne muscular dystrophy (Duchenne), announced that Founding President and CEO Patricia Furlong was named one of WebMD's 2010 Health Heroes. (Logo: http://photos.prnewswire.com/prnh/20100119/DC39975LOGO) (Logo: http://www.newscom.com/cgi-bin/prnh/20100119/DC39975LOGO) Ms. Furlong is one of six...

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2010-10-19 09:25:00

Viagra, the famous little blue pill that millions of men use for erectile dysfunction, and originally developed to help ailing hearts, may now also help treat heart symptoms of muscular dystrophy, according to researchers Monday. Mice that were genetically engineered to have a condition similar to Duchenne muscular dystrophy were tested and scientists found the drug could improve how the heart works, according to their research. Joseph Beavoa of the University of Washington and colleagues...

2010-10-15 17:13:40

Implications for autoimmune and neurological diseases How a T cell decides to make protein X, Y, or Z can have profound effects for fighting foreign invaders or staving off dire autoimmune reactions. Researchers at the University of Pennsylvania School of Medicine have identified the steps that control how different forms of an immune cell protein called CD45, which is critical for activating the immune system when faced with pathogens, are controlled in the arc of a body's immune response....

2010-10-08 01:58:14

Natural immunity to dystrophin may contribute to muscle disease and complicate experimental therapies An immune reaction to dystrophin, the muscle protein that is defective in patients with Duchenne muscular dystrophy, may pose a new challenge to strengthening muscles of patients with this disease, suggests a new study appearing in the October 7, 2010, issue of The New England Journal of Medicine. Duchenne muscular dystrophy (DMD) is a hereditary and lethal neuromuscular disease characterized...

2010-10-05 11:00:00

After 5 Years at White Rock Lake, Local Outreach Effort and Fundraiser Moves to a Larger Stage DALLAS, Oct. 5 /PRNewswire-USNewswire/ -- John Killian, Chairman of Parent Project Muscular Dystrophy (PPMD), the largest non-profit organization in the United States focused on finding a cure for Duchenne muscular dystrophy (Duchenne), and his wife Stefanie Killian, announced today that the 6th Annual Sam's Day will take place on October 30, 2010 from 11am to 5pm at NorthPark Center in Dallas....

2010-09-25 00:32:36

Researchers report this month that MALAT1, a long non-coding RNA that is implicated in certain cancers, regulates pre-mRNA splicing "“ a critical step in the earliest stage of protein production. Their study appears in the journal Molecular Cell. Nearly 5 percent of the human genome codes for proteins, and scientists are only beginning to understand the role of the rest of the "non-coding" genome. Among the least studied non-coding genes "“ which are transcribed from DNA to RNA...

2010-09-15 19:11:46

Albert Einstein College of Medicine findings mark key advance in using microscopy to reveal secrets of living cells By constructing a microscope apparatus that achieves resolution never before possible in living cells, researchers at Albert Einstein College of Medicine  of Yeshiva University have illuminated the molecular interactions that occur during one of the most important "trips" in all of biology: the journey of individual messenger Ribonucleic acid (RNA) molecules from the...

2010-09-03 07:47:00

$11 Million Supports Five-Year Study to Compare Treatments ROCHESTER, N.Y., Sept. 3 /PRNewswire-USNewswire/ -- A large international study aimed at improving the care of muscular dystrophy patients worldwide is being launched by physicians, physical therapists, and researchers at the University of Rochester Medical Center. Neurologist Robert "Berch" Griggs, M.D., is heading the study of treatments for Duchenne muscular dystrophy, the most common form of the disease that affects children....

2010-07-12 13:26:46

Antisense oligonucleotides delivered into spinal cords of adult and neonatal mice provide a long term rescue from disease symptoms The devastating, currently incurable motor-neuron disease spinal muscular atrophy (SMA) might soon be treated with tiny, chemically modified pieces of RNA called antisense oligonucleotides (ASOs). Scientists at Cold Spring Harbor Laboratory (CSHL) and California-based Isis Pharmaceuticals have succeeded in reversing symptoms of Type III SMA, a relatively mild form...


Word of the Day
tesla
  • The unit of magnetic flux density in the International System of Units, equal to the magnitude of the magnetic field vector necessary to produce a force of one newton on a charge of one coulomb moving perpendicular to the direction of the magnetic field vector with a velocity of one meter per second. It is equivalent to one weber per square meter.
This word is named for Nikola Tesla, the inventor, engineer, and futurist.