Latest Spliceosome Stories
The devastating, currently incurable motor-neuron disease spinal muscular atrophy (SMA) might soon be treated with tiny, chemically modified pieces of RNA called antisense oligonucleotides (ASOs).
Conference Includes Launch of First-Ever Duchenne Therapeutic Development Meeting MIDDLETOWN, Ohio, June 18 /PRNewswire-USNewswire/ -- Patricia A.
A bacteria that lives in hot springs in Japan may help solve one of the mysteries of the early evolution of complex organisms.
Rep. Thomas R.
MIDDLETOWN, Ohio, May 7 /PRNewswire-USNewswire/ -- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and the National Institute of Neurological Disorders and Stroke (NINDS) are launching a five-year, $7.5 million natural history study of Duchenne muscular dystrophy (Duchenne), a degenerative genetically-linked neuromuscular disease.
Using a new approach to studying the spliceosome, a team led by University of Michigan chemistry and biophysics professor Nils Walter, collaborating closely with a team led by internationally recognized splicing experts John Abelson and Christine Guthrie of the University of California, San Francisco, spied on the splicing process in single molecules.
Fundraising Event Will Benefit Duchenne Muscular Dystrophy OAK LAWN, Ill., March 4 /PRNewswire-USNewswire/ -- On Friday, March 12, 2010, The Oak Lawn Community High School Spartans gym will be transformed into its own Dancing with the Stars when for one night only, the gym will become Dancing with the Spartans.
Now researchers at the Stanford University School of Medicine have shown that this tuning process is accomplished in part by restricting the number of messages, called transcripts, produced from each gene.
A novel finding, described today (Feb. 4) on the Science Express Web site by teams from the National Cancer Institute, The University of Texas Health Science Center at San Antonio and the University of Toronto, offers a clue as to how genes can have what you might call multiple personalities.
Research on the genetic defect that causes myotonic muscular dystrophy has revealed that the mutation disrupts an array of metabolic pathways in muscle cells through its effects on two key proteins.
- A coin originally worth six pennies Scots, and later three; held equivalent to an English halfpenny.
- (in plural) Money; cash.