Latest statin therapy Stories

Up to 75 per cent of patients who take statins to treat elevated cholesterol levels may suffer from muscle pain. Scientists at the Center for Healthy Aging at the University of Copenhagen have now identified a possible mechanism underlying this unfortunate side effect. The results have just been published in the well-reputed Journal of American College of Cardiology. Statin is a class of drugs which are used to treat high levels of blood cholesterol by way of inhibiting the liver’s...

Although some studies have suggested that use of lipid-lowering therapies may increase the risk of pancreatitis, an analysis that involved pooling of data from previous studies and included more than 150,000 participants found that statin therapy was associated with a reduction in the risk of pancreatitis in patients with normal or mildly elevated triglyceride levels, according to an article in the August 22/29 issue of JAMA. "Pancreatitis has a clinical spectrum ranging from a mild,...

PARIS and TARRYTOWN, New York, July 20, 2012 /PRNewswire/ -- Sanofi (EURONEXT: SAN and NYSE: SNY) and Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) announced today that several trials within ODYSSEY, the Phase 3 clinical program of SAR236553/REGN727, have initiated patient enrollment. SAR236553/REGN727 is a potential first-in-class, subcutaneously administered, fully-human antibody that lowers low-density lipoprotein (LDL) cholesterol by targeting PCSK9 (proprotein convertase...

LONDON, May 28, 2012 /PRNewswire/ -- THIS RELEASE IS INTENDED EXCLUSIVELY FOR EUROPEAN MEDIA Data presented today from the VOYAGER study demonstrate the benefits of aggressive statin therapy with CRESTOR(TM) (rosuvastatin) in comparison to atorvastatin and simvastatin in high risk patients. VOYAGER is an individual patient data meta-analysis of 32 258 patients from 37 randomised studies, comparing the effects of statin therapy with CRESTOR(TM) (rosuvastatin) to that of...

Statins prevent cancer and reduce death from all causes in heart transplant recipients. The findings were independent of cholesterol levels. The research was presented at the Heart Failure Congress 2012, 19-22 May, in Belgrade, Serbia. The Congress is the main annual meeting of the Heart Failure Association of the European Society of Cardiology. Cancer is the leading cause of death late after heart transplantation. Skin cancer is particularly common, but solid organ cancers including...

(Ivanhoe Newswire) - Cancer is the leading cause of death late after heart transplantation. Now, new research shows that statins, immunomondulatory drugs, may benefit patients beyond their lipid lowering effects. Researchers in Zurich are currently investigating the impact of statin therapy on the occurrence of cancer and death from causes in heart transplantation recipients. They found the increased rate of cancer in heart transplant recipients may be related to the immune suppression of...

Study highlights importance of therapy compliance to reduce cardiovascular disease mortality Patients with rheumatoid arthritis (RA) who discontinue use of statin therapy are at increased risk of death from cardiovascular disease and other causes. According to the findings of a population-based study now available in Arthritis Care & Research, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR), RA patients should be advised of the importance...

Levels of non-high-density lipoprotein cholesterol (non-HDL-C) among statin-treated patients appears to be associated with the risk of developing a major cardiovascular event, such as a heart attack or stroke, as are levels of low-density lipoprotein cholesterol (LDL-C) and apolipoprotein B, according to a meta-analysis of data from previously published studies appearing in the March 28 issue of JAMA. "Statin therapy is the cornerstone of pharmacological therapy for the primary and...

Patients who see evidence of their disease are more likely to adhere to statin therapy, weight loss regimen It seems a picture is worth more than a thousand words for people who see evidence of coronary artery disease, which is the most common type of heart disease in men and women. Simply seeing a build-up of calcium in the walls of the arteries appears to prompt patients to better adhere to both statin therapy and recommendations for weight loss, according to research presented today at...