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Latest Statin Stories

2012-11-12 11:58:24

New research suggests that statins, traditionally used for cholesterol lowering, could be used in the management of individuals who are at risk for developing clotting because they have autoimmune antiphospholipid antibodies (aPL). The research will be presented in two presentations at the annual meeting of the American College of Rheumatology/Association of Rheumatology Health Professionals (ACR/ARHP). The meeting will be held Nov. 9-14, in Washington D.C. "What we have shown is that...

2012-11-07 16:26:52

BOSTON, Nov. 7, 2012 /PRNewswire/ -- ARI-3037MO was well tolerated in single and repeat ascending dose trials in healthy volunteers ARI-3037MO did not provoke flushing or any other treatment-related adverse effects in 58 healthy male and female volunteers ARI-3037MO was well absorbed orally and plasma levels demonstrated good dose proportionality ARI-3037MO showed encouraging lipid changes in both clinical trials in healthy subjects Arisaph Pharmaceuticals, Inc. announced today during...

New Drug Helps Lower High Cholesterol
2012-11-07 07:57:10

April Flowers for redOrbit.com - Your Universe Online Statins are the first line of defense for many people with high cholesterol. For some patients, however, statins do not reduce their low-density lipoprotein cholesterol (LDL) levels. LDL is considered the "bad cholesterol." Some patients' bodies are unable to tolerate statins, or they simply do not respond sufficiently to the medication. New research from Brigham and Women's Hospital, presented at the 2012 American Heart Association...

2012-11-06 16:28:06

THOUSAND OAKS, Calif., Nov. 6, 2012 /PRNewswire/ -- Amgen (NASDAQ:AMGN) today announced that results from the LAPLACE-TIMI 57 and MENDEL Phase 2 studies evaluating AMG 145 in hypercholesterolemic patients with or without statins, respectively, showed that treatment with AMG 145 resulted in a statistically significant reduction in low-density lipoprotein (LDL) cholesterol. The two studies were presented today at the American Heart Association Scientific Sessions 2012 and simultaneously...

2012-11-05 16:24:19

THOUSAND OAKS, Calif., Nov. 5, 2012 /PRNewswire/ -- Amgen (NASDAQ:AMGN) today announced that treatment with AMG 145 in combination with statin therapy, with or without ezetimibe, resulted in a reduction in low density lipoprotein cholesterol (LDL-C), or "bad" cholesterol, by up to 56 percent in patients with heterozygous familial hypercholesterolemia (HeFH) in the Phase 2 RUTHERFORD study. AMG 145 is an investigational fully human monoclonal antibody directed against PCSK9, a protein that...

2012-11-05 08:32:10

PARIS and TARRYTOWN, N.Y., Nov. 5, 2012 /PRNewswire/ -- Sanofi (EURONEXT: SAN and NYSE: SNY) and Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that the ODYSSEY OUTCOMES trial, a Phase 3 cardiovascular outcomes trial (CVOT) with SAR236553/REGN727 is now recruiting patients. SAR236553/REGN727 is an investigational subcutaneously administered, fully-human antibody that is being evaluated for its impact on lowering low-density lipoprotein cholesterol (LDL-C) by targeting PCSK9...

2012-11-05 08:28:08

FRAMINGHAM, Mass., Nov. 5, 2012 /PRNewswire/ -- Boston Heart Diagnostics (BHD), a pioneer in personalized diagnostics and care plans for patients with heart disease, was just named one of the top places to work in Massachusetts by the Boston Globe. BHD ranked 27 out of 40 companies named in the "medium employers" category (companies employing 100 to 249). This is yet another confirmation of the company's growing stature and reputation. Last month, Boston Heart was named as a "Rising...

Hereditary High Blood Cholesterol Overlooked By Health Community
2012-11-02 10:00:25

Connie K. Ho for redOrbit.com — Your Universe Online A new study from the University of Copenhagen recently revealed that high blood cholesterol is a serious hereditary disease that has been overlooked and has not been given effective treatments as compared to other illnesses. In particular, the scientists discovered that there are more Danes who have high blood cholesterol than previously thought. They believe that few individuals and families with the disease have been...

2012-10-31 15:25:55

PARIS and TARRYTOWN, N.Y., Oct. 31, 2012 /PRNewswire/ -- Sanofi (EURONEXT: SAN and NYSE: SNY) and Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that results from a Phase 2 trial of SAR236553/REGN727 in patients with primary hypercholesterolemia were published in the October 31, 2012 issue of the New England Journal of Medicine. The study enrolled patients with primary hypercholesterolemia with elevated LDL-C (greater than or equal to 100 mg/dL) who were on a stable low dose...

Cholesterol Increased By Resistin Protein
2012-10-29 04:32:28

redOrbit Staff & Wire Reports - Your Universe Online In a discovery that could help prevent and treat heart disease, a team of Canadian researchers say that they have found a protein that can increase the production of low-density lipoprotein (LDL) cholesterol. The scientists, who presented their findings Sunday at the Canadian Cardiovascular Congress in Toronto, said that resistin, which is secreted by fatty tissue, causes human liver cells to produce more LDL, known as the "bad"...