Latest Steatohepatitis Stories

2009-11-24 16:25:45

Impaired oxidation in liver associated with progression to NASH A recent metobolomics study by researchers from Virginia Commonwealth University Medical Center in Richmond found that impaired peroxisomal oxidation of polyunsaturated fatty acids (PUFA) is associated with the progression of nonalcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis (NASH). The study also found significantly higher plasma monounsaturated fatty acids in the blood of patients with NAFL and NASH. Full findings...

2009-10-20 13:59:15

Patients with chronic hepatitis C and advanced liver disease who drink three or more cups of coffee per day have a 53% lower risk of liver disease progression than non-coffee drinkers according to a new study led by Neal Freedman, Ph.D., MPH, from the National Cancer Institute (NCI). The study found that patients with hepatitis C-related bridging fibrosis or cirrhosis who did not respond to standard disease treatment benefited from increased coffee intake. An effect on liver disease was not...

2009-10-12 05:30:00

NOVATO, Calif., Oct. 12 /PRNewswire-FirstCall/ -- Raptor Pharmaceutical Corp. ("Raptor" or the "Company") (Nasdaq: RPTPD), announced positive findings from the completed treatment phase of its open-label Phase 2a clinical trial of delayed-release cysteamine bitartrate ("DR Cysteamine") in adolescent patients with non-alcoholic steatohepatitis ("NASH"), a progressive form of liver disease believed to affect 2% to 5% of the U.S. population. At the completion of the initial six-month...

2009-10-01 21:00:00

NEW YORK, Oct. 1 /PRNewswire/ -- Intercept Pharmaceuticals, Inc., has announced that its first-in-class farnesoid X receptor (FXR) agonist INT-747 has met the primary endpoint of improved insulin sensitization in a 6 week double blind, placebo controlled trial in type 2 diabetic patients with nonalcoholic fatty liver disease (NAFLD). By employing a euglycemic insulin clamp procedure, the study demonstrated that a single oral daily dose of INT-747 statistically significantly improved...

2009-06-01 14:58:27

The latest research in liver disease being presented at Digestive Disease Week® 2009 (DDW®) has important implications for tracking disease development in patients and for current and future transplant recipients. Researchers are making great strides in diagnosing and treating liver disease."The research being presented during DDW shows how widespread our efforts are in understanding and treating liver disease," said Brent Tetri, MD, Saint Louis University....

2009-05-29 07:58:51

Intestinal permeability and an overgrowth of bacteria in the small intestine are both associated with nonalcoholic fatty liver disease (NAFLD). These findings are revealed in a new study in the June issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). The article is also available online at Wiley Interscience (www.interscience.wiley.com).Previous studies have suggested that bacteria from the intestine...

2009-02-05 05:30:00

Study Evaluating Cysteamine in Collaboration with UC San Diego NOVATO, Calif., Feb. 5 /PRNewswire-FirstCall/ -- Raptor Pharmaceuticals Corp. ("Raptor" or the "Company") (OTC Bulletin Board: RPTP), today announced the completion of patient enrollment in its Phase 2a open-label clinical trial to evaluate cysteamine bitartrate ("cysteamine") in patients diagnosed with non-alcoholic steatohepatitis ("NASH"). NASH, a progressive form of liver disease that accounts for approximately 10% of newly...

2008-12-08 08:21:27

Obesity is becoming one of the most common causes of liver disease in the nation. A popular surgery may resolve the dangerous disease and its cause. A recent study shows bariatric surgery, a popular and effective weight loss method for morbidly obese individuals, improves or completely resolves complications associated with nonalcoholic fatty liver disease (NAFLD) in a majority of patients. Of patients with steatosis, or fat accumulation in the liver cells, 91.6 experienced improvement or...

2008-11-03 15:00:06

Enzo Biochem, Inc. (NYSE:ENZ) reported today that recent work supported by Enzo will be presented at the Liver Conference(R), sponsored by the American Society for the Study of Liver Diseases (ASSLD), detailing research advances in understanding Natural Killer cells (NKT cells) -- lymphocytes that play a major role in immune surveillance and are involved in important processes such as autoimmunity and cancer. The research presented focuses on the following key areas involving NKT...

2008-10-27 09:00:12

SAN FRANCISCO, Oct. 27 /PRNewswire/ -- Nonalcoholic steatohepatitis (NASH) is strongly associated with obesity, and there is no approved medical therapy for this chronic progressive liver disease. Researchers tested the effects of weight reduction using a state-of-the-art lifestyle intervention program. To do so, 31 overweight or obese patients with NASH were randomized into two groups. Subjects in the first group were put on a lifestyle intervention program consisting of diet, exercise, and...

Word of the Day
  • A murmuring sound; a rushing or whistling sound, like that of the wind; a deep sigh.
  • A gentle breeze; a waft; a breath.
  • Any rumor that engages general attention.
  • A cant or whining mode of speaking, especially in preaching or praying; the chant or recitative characteristic of the old Presbyterians in Scotland.
  • To make a rushing, whistling, or sighing sound; emit a hollow murmur; murmur or sigh like the wind.
  • To breathe in or as in sleep.
  • To utter in a whining or monotonous tone.
According to the OED, from the 16th century, this word is 'almost exclusively Scots and northern dialect until adopted in general literary use in the 19th.'