Latest Stem cell factor Stories
(Ivanhoe Newswire) – Turning back the clock on aging! Could it be possible? Scientists say with the help of stem cells, we could be closer than we think. Scientists at Cincinnati Children's Hospital Medical Center and the Ulm University Medicine in Germany bring new perspective to what has been a life science controversy – countering what used to be broad consensus that the aging of hematopoietic stem cells (HSCs) was locked in by nature and not reversible by therapeutic intervention....
Researchers have rejuvenated aged hematopoietic stem cells to be functionally younger, offering intriguing clues into how medicine might one day fend off some of the ailments of old age. Scientists at Cincinnati Children's Hospital Medical Center and the Ulm University Medicine in Germany report their findings online May 3 in the journal Cell Stem Cell. The paper brings new perspective to what has been a life science controversy – countering what used to be broad consensus that the aging...
CINCINNATI, May 3, 2012 /PRNewswire-USNewswire/ -- Researchers have rejuvenated aged hematopoietic stem cells to be functionally younger, offering intriguing clues into how medicine might one day fend off some of the ailments of old age. (Logo: http://photos.prnewswire.com/prnh/20110406/MM79025LOGO) Scientists at Cincinnati Children's Hospital Medical Center and the Ulm University Medicine in Germany report their findings online May 3 in the journal Cell Stem Cell. The...
New research shows it may be no accident when doctors observe how patients suffering from both breast cancer and arthritis seem to have more aggressive cancer. However, the new-found interaction between the two diseases may also suggest a possible treatment. A potential relationship between metastatic breast cancer and autoimmune arthritis, as suggested by past epidemiological studies, has led researchers from the University of North Carolina at Charlotte to perform a series of mouse model...
SAN DIEGO, Dec. 13, 2011 /PRNewswire/ -- Fate Therapeutics, Inc. announced today promising clinical results from a Phase 1b trial of ProHema (FT1050-enhanced umbilical cord blood) as part of double-umbilical cord blood (UCB) transplants in adult patients with hematologic malignancies who have undergone reduced-intensity conditioning therapy. The data are being presented at the 53rd annual American Society of Hematology (ASH) meeting, being held December 10-13, in San Diego,...
All stem cells—regardless of their source—share the remarkable capability to replenish themselves by undergoing self-renewal. Yet, so far, efforts to grow and expand scarce hematopoietic (or blood-forming) stem cells in culture for therapeutic applications have been met with limited success. Now, researchers at the Stowers Institute for Medical Research teased apart the molecular mechanisms enabling stem cell renewal in hematopoietic stem cells isolated from mice and successfully...
The bone marrow stem cells responsible for generating new blood cells are less fixed and more flexible than previously thought, according to a paper published online on February 7 in the Journal of Experimental Medicine (www.jem.org).Some earlier studies suggested that these hematopoietic stem cells (HSCs) come in two distinct varieties: those that remain dormant during times of health but possess the ability to regenerate the whole blood system after trauma such as irradiation or...
Understanding how blood stem cells are maintained within the niche offers new opportunities to exploit them therapeuticallyHematopoietic stem cells (HSCs) have two unique abilities that are prized by medical researchers: to self-renew and to develop into any kind of blood cell, which enables them to replenish the entire blood and immune system. Scientists have traced these qualities to a distinct locale or niche within the bone marrow that HSCs home in on, but the identity and function of the...
ATLANTA, March 16 /PRNewswire/ -- CorMatrix Cardiovascular, Inc., a medical device company dedicated to developing and delivering unique extracellular matrix (ECM) biomaterial devices that harness the body's innate ability to repair damaged cardiovascular tissue, announced today that investigators from the Mercer University School of Medicine, Emory University and CorMatrix Cardiovascular, Inc. demonstrated that an injectable emulsion of the company's ECM Technology enhances angiogenesis...
Biologists at UC San Diego have identified the specific region in vertebrates where adult blood stem cells arise during embryonic development.Their discovery, which appears in a paper in this week's early online edition of the journal Nature, is a critical first step for the development of safer and more effective stem cell therapies for patients with leukemia, multiple myeloma, anemia and a host of other diseases of the blood or bone marrow.The researchers say their time-lapse imaging of the...
