Latest Steven Nissen Stories

2008-07-02 00:05:00

Speaking before a U.S. advisory panel, Cleveland Clinic cardiologist Steven Nissen said higher standards of testing should be enforced to ensure that new proposed diabetes medicines do not damage patients' hearts. "We have to rule out some level of harm prior to approval," Cleveland Clinic cardiologist Steven Nissen told the panel of experts that advises the Food and Drug Administration. Some experts claim that stricter regulation may require longer clinical testing periods, which could slow...

2008-01-31 10:20:00

Iowa Senator Charles Grassley said yesterday that Dr. Steven M. Haffner, a well-known diabetes expert at the University of Health Science Center in San Antonio, had leaked confidential, unpublished information to GlaxoSmithKline (GSK) that questioned the safety of the company's diabetes drug Avandia.A New York Times report said that Dr. Haffner had faxed the document, a medical journal article he had agreed to read as part of the normal prepublication peer review process for The New England...

2007-05-23 14:30:00

How does a drug go from blockbuster to bust? How can big safety issues go undetected in medicines taken by millions of people for many years, as happened this week with the diabetes pill Avandia and a few years ago with the painkiller Vioxx? Or with devices like drug-coated stents, which came under a cloud last year after 6 million heart patients had already received them? All roads - and fingers this week - point to the U.S. Food and Drug Administration. From a company's labs to a consumer's...

2006-09-04 08:06:34

By Ben Hirschler, European Pharmaceuticals Correspondent BARCELONA (Reuters) - The booming market for drug-coated stents faces an uncertain future as some heart experts question the long-term safety record of the devices. Controversy about the tiny, wire-mesh tubes used to prop open clogged arteries has been fueled by studies at this week's World Congress of Cardiology suggesting they carry a higher risk of potentially fatal blood clots than older bare metal stents. Drug-coated...

2005-11-21 12:08:05

By Susan Heavey WASHINGTON (Reuters) - An experimental diabetes drug that may increase the risk of congestive heart failure and death should not be allowed on the market despite initial support from U.S. regulators, a consumer group said on Monday. Public Citizen's Health Research Group called on the U.S. Food and Drug Administration to hold off approving Pargluva, made by Bristol-Myers Squibb Co. and Merck & Co Inc., without "at the very least" a five-year clinical safety...

2005-10-20 14:59:04

By Andrew Stern CHICAGO (Reuters) - The experimental diabetes drug, Pargluva, made by Merck & Co. Inc. and Bristol-Myers Squibb, may carry risks of heart attack and cancer and should be studied further, researchers said on Thursday. Dr. Steven Nissen, one of the Cleveland Clinic researchers who five years ago publicized the similar heart risk posed by Merck's painkiller, Vioxx, said he analyzed the same data that led a U.S. Food and Drug Administration advisory panel last month...

2005-10-20 11:36:53

CHICAGO (Reuters) - The experimental diabetes drug Pargluva, made by Merck and Co. Inc. and Bristol-Myers Squibb, may carry risks for heart attacks and cancer and should be studied further, researchers said on Thursday. Of the diabetic patients who took the drug in company-funded trials, 1.47 percent suffered a heart attack, a stroke or died, more than double the rate among those taking a placebo or an already approved drug, Cleveland Clinic researcher Steven Nissen wrote in the...

Word of the Day
  • One of a religious order living in a convent or in community; a monk: opposed to anchoret or hermit (one who lives in solitude).
  • A social bee.
This word comes from the Latin 'coenobium,' convent, which comes from the Greek 'koinobios,' living in community.