Latest Stress granule Stories
Researchers have tied mutations in a gene that causes amyotrophic lateral sclerosis (ALS) and other neurodegenerative disorders to the toxic buildup of certain proteins and related molecules in cells, including neurons.
Researchers have shown that an ALS-related protein is involved in clearing RNA-containing material that builds up in cells, including neurons.
Several genes have been linked to ALS, with one of the most recent called FUS.
A Jackson Laboratory research team, working in collaboration with researchers at Brigham and Womenâ€™s Hospital and Harvard Medical School in Boston, show that RNA granules--key players in messenger RNA (mRNA) processing--can affect eye development, leading to juvenile cataracts in humans and mice.
- A pivoted catch designed to fall into a notch on a ratchet wheel so as to allow movement in only one direction (e.g. on a windlass or in a clock mechanism), or alternatively to move the wheel in one direction.