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Last updated on April 16, 2014 at 14:37 EDT

Latest Structural Genomics Consortium Stories

2014-03-05 08:29:31

Joint Publication Identifies Clinical Kinase Inhibitors that Potently Cross React with Bromodomain Epigenetic Reader Proteins OXFORD, United Kingdom and FREMONT, Calif., March 5, 2014 /PRNewswire/ -- The Structural Genomics Consortium (SGC) and DiscoveRx Corporation today announced the publication of findings that suggest compelling new multi-targeting approaches for cancer therapy. In a study entitled "Dual kinase-bromodomain inhibitors for rationally designed polypharmacology,"...

2012-07-19 02:25:49

CARLSBAD, Calif., July 19, 2012 /PRNewswire/ -- Life Technologies Corporation (NASDAQ: LIFE) today announced it has signed a collaborative partnership with the Structural Genomics Consortium (SGC), and several groups of leading expert scientists in antibody technology at the Universities of Chicago and Toronto, to generate a first-ever master set of quality epigenetic recombinant antibodies for use in disease-related research. The first 58 of 200 highly-specific antibodies to be...

2012-06-04 02:27:14

Antibodies are first released in massive collaboration to create 'master set' of high-quality renewable epigenetics antibodies TORONTO, June 4, 2012 /PRNewswire/ - The Structural Genomics Consortium (SGC), a group of expert researchers in recombinant antibody technology from the Universities of Toronto and Chicago and an industry partner have entered into a pioneering public-private partnership to generate renewable recombinant antibodies for epigenetic targets.  The first set...

2012-02-21 12:32:20

A team of researchers at Karolinska Institutet has generated a map over the effects of small drug-like molecules on PARP1 and other similar proteins in the body. This map may explain the mechanism behind putative side effects of the so-called PARP inhibitors, and can play an important role in the development of novel tailor-made cancer drugs. The study is presented in the journal Nature Biotechnology, and will hopefully contribute to new cancer therapies with fewer detrimental side effects....

2010-09-28 19:09:37

The Structural Genomics Consortium (SGC), an international public-private partnership that aims to determine three-dimensional structures of medically important proteins, announced the release into the public domain of its 1000th high-resolution protein structure. The 1000th structure - known as JmjD2C - belongs to a class of proteins involved in epigenetic signalling, a key research area for the SGC. Epigenetics is the study of inherited changes in gene expression caused by proteins such as...