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Latest Structural Genomics Stories

2014-03-05 08:29:31

Joint Publication Identifies Clinical Kinase Inhibitors that Potently Cross React with Bromodomain Epigenetic Reader Proteins OXFORD, United Kingdom and FREMONT, Calif., March 5, 2014 /PRNewswire/ -- The Structural Genomics Consortium (SGC) and DiscoveRx Corporation today announced the publication of findings that suggest compelling new multi-targeting approaches for cancer therapy. In a study entitled "Dual kinase-bromodomain inhibitors for rationally designed polypharmacology,"...

2013-04-29 20:48:08

Berkeley Lab Researchers Unveil Technique for Easy Comparisons of Proteins in Solution A revolutionary X-ray analytical technique that enables researchers at a glance to identify structural similarities and differences between multiple proteins under a variety of conditions has been developed by researchers with the U.S. Department of Energy (DOE)´s Lawrence Berkeley National Laboratory (Berkeley Lab). As a demonstration, the researchers used this technique to gain valuable new...

2011-09-01 16:55:50

Special journal edition chronicles 3-D structures of important antibacterial and bioterrorist targets The September issue of the online scientific journal Acta Crystallographica: Structural Biology and Crystallization Communications (Acta Cryst F) will consist entirely of work done at the Seattle Structural Genomics Center for Infectious Disease (SSGCID), a consortium of researchers from Seattle BioMed, Emerald BioStructures, the University of Washington and Pacific Northwest National...

2010-12-08 02:27:39

Scientists work together to map and solve 500 protein structures Scientists at Seattle Biomedical Research Institute (Seattle BioMed) and Northwestern University Feinberg School of Medicine have reached a major milestone in the effort to wipe out some of the most lethal diseases on the planet. As leaders of two large structural genomics centers, they've experimentally determined 500 three-dimensional protein structures from a number of bacterial and protozoan pathogens, which could...

2010-10-22 14:03:38

A multi-institutional consortium led by The Scripps Research Institute scientists, the Joint Center for Structural Genomics (JCSG), is the sole focus of a special issue of the journal Acta Crystallographica Section F. This is the first time in the history of the monthly journal, which publishes peer-reviewed crystallography and structural biology articles, that an entire issue is devoted to the works of a single scientific center. The issue contains 35 articles grouped into sections that...

2010-09-28 19:09:37

The Structural Genomics Consortium (SGC), an international public-private partnership that aims to determine three-dimensional structures of medically important proteins, announced the release into the public domain of its 1000th high-resolution protein structure. The 1000th structure - known as JmjD2C - belongs to a class of proteins involved in epigenetic signalling, a key research area for the SGC. Epigenetics is the study of inherited changes in gene expression caused by proteins such as...

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2009-07-21 09:39:42

Scientists at the U.S. Department of Energy's (DOE) Lawrence Berkeley National Laboratory have developed a fast and efficient way to determine the structure of proteins, shortening a process that often takes years into a matter of days. The high-throughput protein pipeline could allow scientists to expedite the development of biofuels, decipher how extremophiles thrive in conditions that kill most organisms, and better understand how proteins carry out life's vital functions. The technique...

2005-07-18 18:23:28

BUFFALO, N.Y. -- A University at Buffalo scientist created a stir in 2003 when he announced a much faster, more precise and far less expensive method of obtaining nuclear magnetic resonance (NMR) data to map a protein's atomic structure. Genomics researchers were fascinated, but some also were a bit skeptical. Not anymore. In the current issue of Proceedings of the National Academy of Sciences, Thomas A. Szyperski, Ph.D., UB professor of chemistry, and a team of structural genomics...


Word of the Day
barratry
  • The offense of persistently instigating lawsuits, typically groundless ones.
  • An unlawful breach of duty on the part of a ship's master or crew resulting in injury to the ship's owner.
  • Sale or purchase of positions in church or state.
This word ultimately comes from the Old French word 'barater,' to cheat.
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