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Last updated on April 18, 2014 at 21:21 EDT

Latest Sulfadoxine Stories

2013-07-24 11:18:04

The main barriers to the access, delivery, and use of interventions that help to prevent malaria in pregnant women are relatively consistent across sub-Saharan African countries and may provide a helpful checklist to identify the factors influencing uptake of these important interventions, according to a study published in this week's PLOS Medicine. The analysis by Jenny Hill and colleagues from the Liverpool School of Tropical Medicine in the UK, the London School of Hygiene &...

2013-02-13 10:34:36

Among pregnant women in sub-Saharan Africa, intermittent preventive therapy for malaria with 3 or more doses of the drug regimen sulfadoxine-pyrimethamine was associated with a higher birth weight and lower risk of low birth weight than the current standard 2-dose regimen, according to a review and meta-analysis of previous studies published in the February 13 issue of JAMA. "Intermittent preventive therapy with sulfadoxine-pyrimethamine to control malaria during pregnancy is used in 37...

2012-07-04 22:53:53

In most comprehensive review of a decade of data researchers confirm indoor insecticide treatments, dramatically reduce malaria; study finds world´s best drug still effective in African malaria 'hot zone' while researchers question for how long A pair of provocative studies in the July 2012 issue of The American Journal of Tropical Medicine and Hygiene (AJTMH) provides a window into the intense ground war now underway against malaria. In one review, researchers offer new evidence...

2012-04-02 20:51:06

Malaria infections among infants can be cut by up to 30 per cent when antimalarial drugs are given intermittently over a 12 month period, a three-year clinical trial in Papua New Guinea has shown. The trial showed the drug regime was effective against both Plasmodium falciparum and Plasmodium vivax malaria, the first time antimalarial drugs have been shown to prevent infections by both species of malaria. The treatment regime, called intermittent preventive treatment (IPT), protected the...

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2009-05-29 15:16:08

The first evidence of resistance to the world's most effective drug for treating malaria has been found by international scientists. The scientists said that the trend in western Cambodia has to be urgently contained because full-blown resistance would be a global health catastrophe. Drugs are taking longer than before to clear blood of malaria parasites. This shows early signs of emerging resistance to a disease that kills a million people each year. The most effective drug cleared all...

2009-04-14 11:23:41

In research published in PLoS Medicine, Cally Roper of the London School of Hygiene & Tropical Medicine and colleagues use genetic analyses to trace the emergence and dispersal of drug-resistant Plasmodium falciparum malaria in Africa. They find that resistance to the antimalarial drug sulfadoxine has emerged independently in multiple sites in Africa during the past 10-20 years, and that the molecular basis of resistance differs between east and west Africa. Given the potential for...

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2009-02-26 07:10:00

A disease once thought to be somewhat under control with the use of prescription drugs is emerging at the Thai-Cambodian border as drug resistant. The World Health Organization said Wednesday the new strain of malaria could "seriously undermine" efforts to bring the disease under control. "Surveillance systems and research studies... are providing new evidence that parasites resistant to artemisinin have emerged along the border between Cambodia and Thailand where workers walk for miles...

2008-08-26 03:00:17

By Cooper, R G Magwere, T Chloroquine (CHQ) is a cheap, relatively well tolerated drug initially developed for the treatment of malaria in the 1930s. CHQ has, however, since accrued a plethora of uses in the treatment and amelioration of several other diseases and conditions because of its lysosomotropic properties. It also has characteristic physiological and systemic effects. This review gives an overview of the history and pharmacology of CHQ, and progresses to consider some of the...

2008-07-25 09:01:18

Q: The label on my prescription bottle (diabetes med) says to avoid prolonged sun exposure. Why? A: Some drugs may cause a photosensitivity reaction (sensitivity to UVA rays of the sun or tanning devices). The result can be an exaggerated sunburn or, more rarely, an allergic reaction with itching and a blister-like eruption. Your best defense is to wear protective clothing and apply a sunscreen that protects against both UVB and UVA rays. Here's an alphabetized list of potentially...

2006-01-20 00:20:00

WASHINGTON -- The World Health Organization asked pharmaceutical companies on Thursday to end the marketing and sale of "single-drug" artemisinin malaria medicines, in order to prevent malaria parasites from developing resistance to the drug. The use of single-drug artemisinin treatment, or "monotherapy," hastens development of resistance by weakening but not killing the parasite, WHO said in new malaria treatment guidelines. "We request pharmaceutical companies to immediately stop marketing...