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Latest Sulfonamides Stories

2012-10-01 12:24:55

Promising new data from trials aimed at delaying resistance to BRAF inhibitors Promising new data on drug combinations to treat metastatic melanoma are presented at the ESMO 2012 Congress of the European Society for Medical Oncology in Vienna. The phase I and II trials focus on combining drugs to slow the development of resistance to drugs that inhibit BRAF, a gene that is mutated in about half of melanomas. Earlier trials with drugs that target BRAF generated excitement for their...

2012-09-05 02:32:00

DEERFIELD, Ill., Sept. 5, 2012 /PRNewswire/ -- Results of a 10-week, phase 3 study published online in the American Journal of Medicine found the clinic systolic blood pressure (SBP) reductions of a fixed-dose combination of azilsartan medoxomil and chlorthalidone were significantly greater at six and ten weeks than those of azilsartan medoxomil co-administered with hydrochlorothiazide. Data also showed that more patients achieved their target blood pressure levels at the end of...

2012-07-22 10:21:11

WASHINGTON, July 22, 2012 /PRNewswire/ -- Kowa Pharmaceuticals America, Inc. (Kowa Pharmaceuticals) and Eli Lilly and Company (Lilly) (NYSE: LLY) today released results from a pharmacokinetic (PK) study exploring potential drug interaction between the cholesterol medication pitavastatin (LIVALO) 4 mg and the protease inhibitor (PI) combination darunavir/ritonavir (Prezista(®)/Norvir(®)) 800mg/100mg in healthy volunteers.(1) The study, presented at the 19(th) International AIDS...

2012-07-13 10:43:05

Although acetazolamide is widely prescribed to prevent and treat acute mountain sickness (AMS), the appropriate dose at which it is effective and safe has not been clearly defined. A comprehensive review and meta-analysis of 24 studies comparing the efficacy and risks associated with increasing doses of acetazolamide is published in High Altitude Medicine & Biology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers (http://www.liebertpub.com). The article is available free...

2012-03-01 13:49:00

St. Jude Children's Research Hospital scientists discover key enzyme structure in bacteria, a finding that lays the foundation for a new generation of antibiotics that are safer and less prone to drug resistance MEMPHIS, Tenn., March 1, 2012 /PRNewswire-USNewswire/ -- More than 70 years after the first sulfa drugs helped to revolutionize medical care and save millions of lives, St. Jude Children's Research Hospital scientists have determined at an atomic level the mechanism these...

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2011-12-05 21:41:25

Young pigs are known to be particularly susceptible to intestinal problems, which not only discomfort the animals but also slow their growth — and thus increase the cost of meat production.  The most common cause of intestinal problems in suckling pigs is the parasite Isospora suis, which according to the literature can be treated by a class of drugs known as sulfonamides. Anja Joachim and colleagues at the University of Veterinary Medicine, Vienna (Vetmeduni Vienna) have...

2011-06-28 07:30:00

CORK, Ireland, June 28, 2011 /PRNewswire/ -- Tibotec Pharmaceuticals today announced that it has entered into a license agreement with Gilead Sciences, Inc., for the development and commercialization of a new once-daily single tablet fixed-dose antiretroviral combination product containing Tibotec's protease inhibitor PREZISTA® (darunavir) and Gilead's cobicistat, an investigational pharmacoenhancing or "boosting" agent. PREZISTA, co-administered with ritonavir...

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2010-12-15 06:00:00

The US government on Tuesday removed the artificial sweetener saccharin, long believed to potentially be a cancer-causing substance, from its list of hazardous substances. The Environmental Protection Agency (EPA) said the decision was made after studies found the white powdered substance that is 300 times sweeter than sugar "is no longer considered a potential" health hazard to humans. Saccharin, which is used to artificially sweeten thousands of low-calorie beverages and chewing gum, and...

2010-09-22 09:49:22

(Ivanhoe Newswire) "“ Higher clinical drop-out rates among women are a concern when testing for effectiveness of HIV treatments. This new landmark study showed that after recruiting and keeping women in the study, there are no major gender differences in the effectiveness of treating HIV. Previously, women were dropping out of the GRACE study (Gender, Race, and Clinical Experience) like flies, for reasons that weren't due to the ineffectiveness of the drug. This showed that there...

2010-06-14 07:00:00

MALVERN, Pa., June 14 /PRNewswire/ -- Arlington Medical Resources (AMR), a provider of premier market intelligence for the pharmaceutical and diagnostic imaging industries, finds that electrical cardioversion (ECV) usage patterns in Europe differed dramatically by country in the fourth quarter of 2009. While ECV represented almost half of all cardioversion attempts in Germany, in Spain ECV accounted for only 13% of cardioversion attempts. Among the five countries studied, cardioversion...