Latest Survivin Stories

2010-02-16 11:05:46

One of the difficulties of fighting cancer is that drugs often hit other non-cancerous cells, causing patients to get sick. But what if researchers could sneak cancer-fighting particles into just the cancer cells? Researchers at the Georgia Institute of Technology and the Ovarian Cancer Institute are working on doing just that. In the online journal BMC Cancer they detail a method that uses hydrogels - less than 100 nanometers in size - to sneak a particular type of small interfering...

2009-09-16 09:23:41

Yes-associated protein (YAP) is a type of cellular adaptor protein and transcriptional co-activator. In recent years, some investigators have found YAP to be overexpressed and highly activated in hepatic cancers and mammary cancers, suggesting its tumorigenicity. Survivin is a new member of the inhibitor of apoptotic protein (IAP) family, which was initially cloned by the cDNA of the effector cell protease receptor-1 in the human genomic library in 1997. A research team led by Professor Yan...

2009-03-20 07:04:00

COPENHAGEN, March 20 /PRNewswire/ -- Santaris Pharma announced today that the fourth LNA-based drug has been brought into the clinic. In the USA several patients with cancer have now been treated with the Company's Survivin inhibitor, which is jointly developed by Santaris Pharma and Enzon Pharmaceuticals. The U.S. Food and Drug Administration (FDA) recently accepted Enzon PharmaӚ­ceutical's Investigational New Drug (IND) application for the use...

2008-08-13 18:00:14

By Vaux, David Proteins that cause cell death in insects are showing promise as anti-cancer drugs. Every second, about a million of our cells complete the process of cell division to generate an extra million cells. To maintain the correct cell number, and so we don't get bigger and bigger, it is necessary that an equal number of cells are removed. Cells are disposed of by an intracellular self-destruct process termed "apoptosis". Since you started reading this article, 100 million cells...

2006-04-02 16:50:00

WASHINGTON -- Nicotine can prevent chemotherapy drugs such as taxol from killing lung cancer cells, researchers reported on Sunday in a finding that may help explain why lung cancer is so difficult to treat in smokers. They said their findings may also suggest that even people who quit smoking but use nicotine supplements, such as patches or gum, may not be helped as much as they should be by cancer therapy. "Our findings are in agreement with clinical studies showing that patients who...

2005-06-03 19:40:23

A University of Alberta research team has discovered important new information they hope will lead to more effective treatments for pulmonary arterial hypertension (PAH)--a deadly form of high blood pressure in the pulmonary arteries caused by uncontrolled cell growth. Therapies are currently limited for a disease that can lead to heart failure and death within a few years. The researchers have shown that Survivin, a protein almost exclusively expressed in cancer, is also heavily expressed...

Word of the Day
  • To talk saucily.
  • Insolent, opprobrious language; impertinent abuse.
This word is Scots in origin and probably imitative.