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Last updated on April 16, 2014 at 5:49 EDT

Latest Synaptic plasticity Stories

2014-02-07 13:03:28

Science paper by IST Austria scientists reports first evidence for “microdomain” coupling at a mature central synapse and explores the implications for synaptic plasticity In research published in this week’s online edition of Science (DOI: 10.1126/science.1244811), postdoc Nicholas Vyleta and Professor Peter Jonas of the Institute of Science and Technology Austria (IST Austria) uncover the existence of loose coupling between calcium channels and release sensors of exocytosis at a...

2014-01-07 23:02:06

Two new publications by a team from Western University of Health Sciences shed further light on the mechanisms of learning and memory, and neuronal degeneration. Pomona, California (PRWEB) January 07, 2014 Two new publications by a team from Western University of Health Sciences shed further light on the mechanisms of learning and memory, and neuronal degeneration. The first paper, “A molecular brake controls the magnitude of long-term potentiation,” by Yubin Wang, Guoqi Zhu, Victor...

2013-12-12 08:30:57

-Preclinical data on novel antidepressant in phase 2b clinical trials presented at American College of Neuropsychopharmacology 52nd Annual Meeting- EVANSTON, Ill., Dec. 12, 2013 /PRNewswire/ -- Naurex Inc. today announced the presentation of preclinical data at the 52nd Annual Meeting of the American College of Neuropsychopharmacology (ACNP) in Hollywood, Fla, showing that its rapid-acting novel antidepressant GLYX-13 enhances synaptic plasticity, its hypothesized mechanism of...

Scientist Describes New Theory Of Synapse Formation In The Brain
2013-10-11 11:57:41

Forschungszentrum Juelich The human brain keeps changing throughout a person's lifetime. New connections are continually created while synapses that are no longer in use degenerate. To date, little is known about the mechanisms behind these processes. Jülich neuroinformatician Dr. Markus Butz has now been able to ascribe the formation of new neural networks in the visual cortex to a simple homeostatic rule that is also the basis of many other self-regulating processes in nature. With this...

2013-10-02 23:03:15

The Brain Injury Association of America (BIAA) announced today that Coleen M. Atkins, Ph.D., has been selected as the winner of the 2013 BIAA Young Investigator Award. Vienna, VA (PRWEB) October 02, 2013 The Brain Injury Association of America (BIAA) announced today that Coleen M. Atkins, Ph.D., has been selected as the winner of the 2013 BIAA Young Investigator Award. The award is presented based on originality of research, promise for making significant contributions to the field of...

2013-08-12 14:12:37

A team of neuroscientists has identified a modification to a protein in laboratory mice linked to conditions associated with Alzheimer's Disease. Their findings, which appear in the journal Nature Neuroscience, also point to a potential therapeutic intervention for alleviating memory-related disorders. The research centered on eukaryotic initiation factor 2 alpha (eIF2alpha) and two enzymes that modify it with a phosphate group; this type of modification is termed phosphorylation. The...

2013-05-30 12:03:56

Breakthrough Could Lead to Better Understanding of Learning and Memory Students preparing for final exams might want to wait before pulling an all-night cram session – at least as far as their neurons are concerned. Carnegie Mellon University neuroscientists have discovered a new intermediate phase in neuronal development during which repeated exposure to a stimulus shrinks synapses. The findings are published in the May 8 issue of the Journal of Neuroscience. It's well known that...

2013-05-16 08:28:17

HAYWARD, Calif., May 16, 2013 /PRNewswire/ -- Scientists at the Center for Learning and Memory, Tsinghua University, Beijing, and the California-based biopharmaceutical company Magceutics, Inc. (www.magceutics.com) have demonstrated a novel therapy for reversing memory decline in mice with Alzheimer's Disease. By increasing brain magnesium levels, they find significant cognitive improvement in advanced stage AD mice. The study is the first to demonstrate a mechanism for reversing cognitive...

2012-02-22 10:25:31

There are a number of drugs and experimental conditions that can block cognitive function and impair learning and memory. However, scientists have recently shown that some drugs can actually improve cognitive function, which may have implications for our understanding of cognitive disorders such as Alzheimer's disease. The new research is reported 21 February in the open-access journal PLoS Biology. The study, led by Drs. Jose A. Esteban, Shira Knafo and Cesar Venero, is the result of...

Mouse Study Sheds Light On Controlling Hunger
2012-02-08 14:40:15

Researchers have revealed that the neural circuits controlling hunger and eating behaviors are also controlled by plasticity. They found that during fasting, the AgRP neurons that drive feeding behaviors actually undergo anatomical changes that cause them to become more active. This effect results in these neurons "learning" to be more responsive to hunger-promoting neural stimuli. "The role of plasticity has generally not been evaluated in neuronal circuits that control feeding...