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Latest Synaptic vesicle Stories

2011-12-01 01:19:21

The most poisonous substance on Earth – already used medically in small doses to treat certain nerve disorders and facial wrinkles – could be re-engineered for an expanded role in helping millions of people with rheumatoid arthritis, asthma, psoriasis and other diseases, scientists are reporting. Their study appears in ACS' journal Biochemistry. Edwin Chapman and colleagues explain that toxins, or poisons, produced by Clostridium botulinum bacteria, cause of a rare but severe...

2011-08-23 21:24:40

A fundamental new discovery about how nerve cells in the brain store and release tiny sacs filled with chemicals may radically alter the way scientists think about neurotransmission — the electrical signaling in the brain that enables everything from the way we move, to how we remember and sense the world. According to the scientists at the University of California, San Francisco (UCSF) who conducted the research, the discovery doesn´t change the players involved so much as it...

2011-06-22 22:43:37

New studies illuminate brain's complex neurotransmission machinery, point to potential source of problems leading to neurodegenerative and psychiatric conditions Two studies featuring research from Weill Cornell Medical College have uncovered surprising details about the complex process that leads to the flow of neurotransmitters between brain neurons -- a dance of chemical messages so delicate that missteps often lead to neurological dysfunction. A recent Nature Neuroscience study led by Dr....

2011-05-25 21:30:11

With every bodily movement"”from the blink of an eye to running a marathon"”nerve cells transmit signals to muscle cells. To do that, nerve cells rely on tiny molecular motors to transport chemical messengers (neurotransmitters) that excite muscles cells into action. It's a complex process, which scientists are still trying to understand. A new study by Syracuse University researchers has uncovered an important piece of the puzzle. The study, published in the April 22 issue of...

2010-11-10 17:27:38

Reclaimed proteins enable the fusion of transmitter vesicles with the cell membrane Neurons communicate via chemical transmitters which they store in the bubble-like synaptic vesicles and release as required. To be able to react reliably to stimulation, neurons must have a certain number of "acutely releasable" vesicles. With the help of a new method, neuroscientists at the Max Planck Institute of Experimental Medicine in Göttingen have now discovered that neurons systematically recycle...

2010-11-03 00:23:04

NJIT Associate Professor Victor Matveev, PhD, in the department of mathematical sciences, was part of a research team that published "N-type Ca2+ channels carry the largest current: Implications for nanodomains and transmitter release," in Nature Neuroscience on Oct. 17, 2010. http://www.nature.com/neuro/journal/v13/n11/abs/nn.2657.html Leading the project, Elise Stanley, PhD, a senior scientist at the Toronto Western Research Institute, said that Matveev's mathematical modeling showed that...

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2010-05-09 07:53:12

The protein that has long been suspected by scientists of being the master switch allowing brains to function has now been verified by an Iowa State University researcher. Yeon-Kyun Shin, professor of biochemistry, biophysics and molecular biology at ISU, has shown that the protein called synaptotagmin1 (Syt1) is the sole trigger for the release of neurotransmitters in the brain. Prior to this research, Syt1 was thought to be a part of the protein structure (not the sole protein) that...

2010-02-10 12:17:43

A new study from The Montreal Neurological Institute and Hospital "“ The Neuro - at McGill University is the first to discover a molecular link between Parkinson's disease and defects in the ability of nerve cells to communicate. The study, published in the prestigious journal Molecular Cell and selected as Editor's Choice in the prominent journal Science, provides new insight into the mechanisms underlying Parkinson's disease, and could lead to innovative new therapeutic strategies....

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2010-01-22 10:58:45

A team of researchers from the Max Planck Institute of Biochemistry, in Germany, led by the Spanish physicist Rub©n Fernández-Busnadiego, has managed to obtain 3D images of the vesicles and filaments involved in communication between neurons. The method is based on a novel technique in electron microscopy, which cools cells so quickly that their biological structures can be frozen while fully active. "We used electron cryotomography, a new technique in microscopy based on ultra-fast...

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2009-12-23 07:06:16

Communication between nerve cells is vital for our bodies to function. Part of this communication happens through vesicles containing signaling molecules called neurotransmitters. The vesicle fuses with the nerve cell membrane; the neurotransmitters are released and quickly recorded by the next nerve cell. It is crucial that new vesicles constantly are produced for the nerve cell communication continuously to take place. If parts of this communication do not work, it leads to nerve pain like...


Word of the Day
humgruffin
  • A terrible or repulsive person.
Regarding the etymology of 'humgruffin,' the OED says (rather unhelpfully) that it's a 'made-up word.' We might guess that 'hum' comes from 'humbug' or possibly 'hum' meaning 'a disagreeable smell,' while 'gruffin' could be a combination of 'gruff' and 'griffin.'