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Latest Synuclein Stories

2014-07-31 12:29:21

AFFiRiS AG presents Phase I data on a first-of-its-kind treatment with support from The Michael J. Fox Foundation NEW YORK and VIENNA, July 31, 2014 /PRNewswire/ -- AFFiRiS AG announced today at a press conference in New York results of AFF008, a Phase I clinical trial of PD01A, a vaccine against Parkinson's disease. PD01A is the first therapy against the protein alpha-synuclein, a promising Parkinson's drug target, to enter clinical testing. The Michael J. Fox...

2014-04-28 08:33:12

EU support boosts development of therapeutic vaccines against Parkinson's and Multiple System Atrophy. AFFiRiS leads consortium. VIENNA, April 28, 2014 /PRNewswire/ -- An international consortium of top European research teams has received significant EU funding for the development of therapeutic vaccines against Parkinson's Disease (PD) and Multiple System Atrophy (MSA). Led by the Austrian biotech company AFFiRiS AG, the consortium will use a novel tandem strategy to advance...

2014-04-23 16:29:24

NEW YORK, April 23, 2014 /PRNewswire-USNewswire/ -- The Michael J. Fox Foundation for Parkinson's Research (MJFF) is launching a new funding program to promote collaborative analysis of subtypes of the protein alpha-synuclein. Aggregating in the cells of all people with Parkinson's disease (PD), alpha-synuclein is a major target for drug development. To advance those efforts, scientists must analyze different species of this protein -- resulting from splicing or post-translational...

2014-02-25 08:33:01

NEW YORK, Feb. 25, 2014 /PRNewswire-USNewswire/ -- The Parkinson's Progression Markers Initiative (PPMI), a large-scale biomarker study sponsored by The Michael J. Fox Foundation for Parkinson's Research (MJFF), is expanding to study individuals with genetic mutations associated with Parkinson's disease (PD). Researchers hope that greater understanding of the biology and clinical features of these participants -- people with or at risk to develop Parkinson's -- will lead to...

2014-01-08 17:05:18

Gladstone findings challenge conventional wisdom; point to new therapeutic strategies The most devastating aspect of Parkinson's disease may not be its debilitating symptoms, which rob its victims of their ability to control their own movement. It may not be the millions around the world and their families who suffer each day from the disease's harmful effects. Instead, it may in fact be that its root causes remain largely a mystery. But now, scientists at the Gladstone Institutes have...

Mannitol Sugar Alcohol Could Be Used To Treat Parkinson’s Disease
2013-06-17 18:38:49

Lee Rannals for redOrbit.com — Your Universe Online Researchers at Tel Aviv University (TAU) say an artificial sweetener could be a potential treatment for Parkinson's disease. According to findings reported in the Journal of Biological Chemistry, mannitol, a common component of sugar-free gum and candy, helps prevent clumps of the protein a-synuclein from forming in the brain, which is a process that is characteristic of Parkinson's disease. The artificial sweetener has been...

2013-04-26 10:24:16

A protein known to be a key player in the development of Parkinson's disease is able to enter and harm cells in the same way that viruses do, according to a Loyola University Chicago Stritch School of Medicine study. The protein is called alpha-synuclein. The study shows how, once inside a neuron, alpha synuclein breaks out of lysosomes, the digestive compartments of the cell. This is similar to how a cold virus enters a cell during infection. The finding eventually could lead to the...

2013-04-08 12:16:35

Research presented at the Genetics Society of America's ongoing annual Drosophila Conference in Washington, D.C., suggests that mannitol, a sugar substitute, could lead to a future treatment for Parkinson's disease Researchers from Tel Aviv University describe experiments that could lead to a new approach for treating Parkinson's disease (PD) using a common sweetener, mannitol. This research is presented today at the Genetics Society of America's 54th Annual Drosophila Research Conference...

2013-03-04 11:17:30

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the most common genetic mutations in familial Parkinson's disease damage brain cells. The study, which published online today in the journal Nature Neuroscience, could also open up treatment possibilities for both familial Parkinson's and the more common form of Parkinson's that is not inherited. Parkinson's disease is a gradually progressing disorder of the nervous system that causes stiffness or...


Word of the Day
caparison
  • A cloth or covering, more or less ornamented, laid over the saddle or furniture of a horse, especially of a sumpter-horse or horse of state.
  • Clothing, especially sumptuous clothing; equipment; outfit.
  • To cover with a caparison, as a horse.
  • To dress sumptuously; adorn with rich dress.
This word ultimately comes from the Medieval Latin 'cappa,' cloak.
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