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Last updated on April 19, 2014 at 18:42 EDT

Latest Systemic scleroderma Stories

2008-06-20 12:00:07

SOUTH SAN FRANCISCO, Calif. and ALLSCHWIL, Switzerland, June 20 /PRNewswire/ -- Actelion Ltd announced today that data published in The Lancet(1) show that, in mildly symptomatic pulmonary arterial hypertension (PAH) patients (WHO functional class II - WHO FC II), bosentan (Tracleer(R)) prevented clinical deterioration by significantly delaying time to clinical worsening and reduced the number of patients worsening to WHO FC III/IV. A significant reduction in pulmonary vascular resistance...

2007-04-13 06:00:14

By Park, Joo Hun; Kim, Dong Soon; Park, I-Nae; Jang, Se Jin; Et al Background: To investigate whether the better prognosis of interstitial pneumonias associated with collagen vascular disease (CVD) compared with idiopathic interstitial pneumonia (IIP) is due to higher frequency of the nonspecific interstitial pneumonia (NSIP) pattern in CVD, we compared the outcomes of patients from these two groups with the same histopathologic pattern. Subjects: The clinical features and survival of 362...

2005-06-29 06:38:13

Scleroderma's symptoms can range from hardened skin to damaged internal organs It's called scleroderma, a disfiguring disorder that causes the skin and internal organs to harden and tighten. Yet few people have heard of or know much about it. But that's not surprising, because medical experts have great gaps in their knowledge of the disease. There's no known cure for scleroderma, and although it's suspected to be an autoimmune disorder, doctors still debate its true cause. But experts agree...

2004-11-26 03:00:11

ABSTRACT: The purpose of this study was to identify hand factors that change over a five-year period that may be risk factors for the development of functional disability in persons with systemic sclerosis (scleroderma). Sixty individuals with scleroderma were administered assessments of grip and pinch strength, joint range of motion, and pain, and were observed for the presence of digital ulcers, digital scars, calcium deposits, puffy fingers, and tendon friction rubs. Matched-pairs chi...

2004-11-26 03:00:10

Cerebellar atrophy has been recognized as an occasional feature of systemic lupus erythematosus (SLE)1,2 but not systemic sclerosis. CASE HISTORY The patient was a woman whose illness had begun at the age of 40 with Raynaud's phenomenon, progressing to distal necrosis and ulceration of fingertips, with sclerosis of the hands, feet and face. The results of investigation were consistent with systemic sclerosis (SS). Subsequently she reported heartburn and regurgitation, and oesophageal...