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Latest Systemic Sclerosis Stories

2013-10-03 16:01:39

2013 classification criteria outperform 1980 measures New classification criteria for systemic sclerosis have just been published and are more sensitive than the 1980 criteria, enabling earlier identification and treatment of this disabling autoimmune disease. The 2013 criteria, developed by a joint committee commissioned by the American College of Rheumatology (ACR) and European League Against Rheumatism (EULAR), are published in the ACR journal, Arthritis & Rheumatism. Systemic...

2012-05-10 09:34:04

Antibodies associated with severe lung disease and decreased survival to blame African Americans have more severe complications from systemic sclerosis, also known as scleroderma, than Caucasians. Findings published today in, Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR), show that compared with Caucasians, African-American patients were more likely to have antibodies that increased frequency and severity of pulmonary fibrosis, which is associated with...

2011-07-12 22:19:22

Systemic scleroderma has slowed Tracy Zinn but it has not stopped her from working. Thanks in part to determination and an accommodating employer, Zinn is now in her 13th year as an account executive for a firm that produces educational software. But, many with the incapacitating disease are not as fortunate. In the United States, the work disability rate for people with systemic scleroderma, also known as systemic sclerosis, is two to three times that of people with some other rheumatic...

2011-05-11 00:35:25

Age and hypertension contribute to coronary calcification -- similar to general population A new study by researchers in Hong Kong suggests that systemic sclerosis is an independent determinant for moderate to severe coronary calcification or atherosclerosis. Conventional cardiovascular risk factors such as age and hypertension predispose patients with systemic sclerosis to plaque build-up in the heart arteries similar to the general population. Details of this study are now available in...

2011-03-08 15:44:12

Modified-release therapy is well tolerated in clinical trial Researchers in Europe reported that treatment with modified-release sildenafil significantly reduced the frequency of attacks of Raynaud's phenomenon in patients with limited cutaneous systemic sclerosis (lcSSc), also known as scleroderma. The double-blind, placebo-controlled trial found that sildenafil was well tolerated with only some subjects experiencing minor or moderate side effects. Full findings are available in the March...

2008-07-01 09:00:12

arGentis Pharmaceuticals, LLC announced today that it has filed a patent application for Nucleic Acid Sequences highly associated with the inability of oral immune tolerance to be induced in some systemic sclerosis (SSc) patients. As explained in the patent application, the identified sequences predict which patients can respond to ARG201, an immunotherapy that induces oral immune tolerance in patients with Late Phase diffuse cutaneous systemic sclerosis. Results from patient DNA samples...

2008-06-30 12:02:16

arGentis Pharmaceuticals, LLC announced today that the Phase II results using highly purified type 1 bovine collagen orally (now known as ARG201) in the treatment of diffuse cutaneous systemic sclerosis (scleroderma - SSc) have been published in the June issue of Arthritis & Rheumatism, a major peer-reviewed rheumatology research journal. Systemic sclerosis is an autoimmune disease causing widespread fibrosis of the skin and internal organs. ARG201 is an immunotherapy that induces low...

2005-06-29 06:38:13

Scleroderma's symptoms can range from hardened skin to damaged internal organs It's called scleroderma, a disfiguring disorder that causes the skin and internal organs to harden and tighten. Yet few people have heard of or know much about it. But that's not surprising, because medical experts have great gaps in their knowledge of the disease. There's no known cure for scleroderma, and although it's suspected to be an autoimmune disorder, doctors still debate its true cause. But experts agree...

2004-11-26 03:00:11

ABSTRACT: The purpose of this study was to identify hand factors that change over a five-year period that may be risk factors for the development of functional disability in persons with systemic sclerosis (scleroderma). Sixty individuals with scleroderma were administered assessments of grip and pinch strength, joint range of motion, and pain, and were observed for the presence of digital ulcers, digital scars, calcium deposits, puffy fingers, and tendon friction rubs. Matched-pairs chi...


Word of the Day
bodacious
  • Remarkable; prodigious.
  • Audacious; gutsy.
  • Completely; extremely.
  • Audaciously; boldly.
  • Impressively great in size; enormous; extraordinary.
This word is probably from the dialectal 'boldacious,' a blend of 'bold' and 'audacious.'
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