Latest Systems biology Stories

Comprehensive understanding of bacteria could lead to new insights into many organismsInvestigators at Burnham Institute for Medical Research (Burnham), University of California, San Diego (UC San Diego), The Scripps Research Institute (TSRI), Genomics Institute of the Novartis Research Foundation (GNF) and other institutions have constructed a complete model, including three dimensional protein structures, of the central metabolic network of the bacterium Thermotoga maritima (T. maritima)....

A report released today by the National Research Council calls on the United States to launch a new multiagency, multiyear, and multidisciplinary initiative to capitalize on the extraordinary advances recently made in biology and to accelerate new breakthroughs that could solve some of society's most pressing problems -- particularly in the areas of food, environment, energy, and health.The report was requested by the National Institutes of Health, National Science Foundation, and U.S....

UCSF researchers have genetically encoded mouse cells to respond to light, creating cells that can be trained to follow a light beam or stop on command like microscopic robots.This is the first time researchers have been able to import a light controlled "on-off switch" from plants into a mammalian cell to instantly control a variety of cell functions, the researchers said. As such, it offers both a powerful new tool in cancer and cardiovascular research, as well as the potential to...

British scientists have uncovered new details about how the cells in our bodies communicate with each other and their environment: findings that are of fundamental importance to human biology.Cells 'talk' to each other through a complex process called 'signaling'. When these signals go wrong, it can lead to all kinds of diseases, including cancer, diabetes and arthritis, to name but a few.Scientists have long been able to see how cells send and receive signals at their outer skins, or...

ST. JOSEPH, Mich., Sept. 8 /PRNewswire/ -- GeneGo, Inc., the leading systems biology tools company, announced today that Proteostasis Therapeutics has licensed its data mining and analysis platform, MetaCore. Proteostasis Therapeutics is the first company dedicated to the discovery of novel small molecule therapeutics based upon understanding the body's Proteostasis Network. The Proteostasis Network maintains the body's natural balance of proteins to protect us from numerous diseases....

ST. JOSEPH, Mich., Sept. 1 /PRNewswire/ -- GeneGo, Inc., the leading systems biology tools company, announced today that it launched a collaborative development project on systems biology of stem cells with global pharmaceutical companies and leading academic centers as members. The 24-month project aims to create a comprehensive "knowledge base" on development and biology of different types of stem cells. The knowledge base will be supported by GeneGo's MetaDiscovery tools and applied in...

UCSF researchers have identified the two key circuits that control a cell's ability to adapt to changes in its environment, a finding that could have applications ranging from diabetes and autoimmune research to targeted drug development for complex diseases.The new findings are featured as the cover story in the August 21, 2009 issue of the journal Cell.The limited number of circuits that can achieve adaptation represents a fundamental shift in our understanding of this important biological...

Researchers at the California Institute of Technology (Caltech) and their colleagues in 30 laboratories worldwide have released a new set of standards for graphically representing biological information"”the biology equivalent of the circuit diagram in electronics. This visual language should make it easier to exchange complex information, so that biological models are depicted more accurately, consistently, and in a more readily understandable way.The new standard, called the Systems...

Researchers at the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) and their colleagues in 30 labs worldwide have released a new set of standards for graphically representing biological information "“ the biology equivalent of the circuit diagram in electronics. This visual language should make it easier to exchange complex information, so that models are accurate, efficient and readily understandable. The new standard, called the Systems Biology...

REDWOOD CITY, Calif., Aug. 11 /PRNewswire/ -- Ingenuity Systems today announced that BD Biosciences, a segment of BD (Becton, Dickinson and Company), is integrating Ingenuity's Knowledge Base and its Search and Pathway Navigation technologies into its new website. By leveraging Ingenuity's biological pathways and molecular networks, BD Biosciences will enable its research customers to quickly and easily identify products and experimental design options most relevant to their research. From...