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Latest Systems biology Stories

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2009-12-28 09:20:00

Scientists of Helmholtz Zentrum Mnchen led by Professor Karsten Suhre have identified new gene variants associated with disturbances in the lipid metabolism. Some of these common human gene variants are already known to be risk factors for diabetes mellitus. The pathomechanisms of diabetes have intrigued physicians and been the subject of much debate for many decades. These new research results may contribute to a better understanding of the clinical picture of diabetes and its pathogenesis...

2009-12-22 13:56:14

No two tumors are alike, but analyzing the genetics of cancers from different parts of the body may reveal surprising details useful for treatment and prevention. That process is already gaining traction at the University of Chicago's Institute for Genomics and Systems Biology (IGSB), where researchers are one year into a three-year project to collect and analyze the genetic sequence and variations of every gene expressed by 1,000 tumors. Over the past year, working closely with physicians,...

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2009-12-10 13:57:44

Brandeis researchers reveal the hidden, transient life of a protein between active states Understanding the incredibly speedy atomic mechanisms at work when a protein transitions from one shape to another has been an elusive scientific goal for years, but an essential one for elucidating the full panoply of protein function. How do proteins transition, or interconvert, between distinct shapes without unfolding in the process? Until now, this question has been a hypothetical one, approached by...

2009-12-09 07:30:00

MILFORD, Mass., Dec. 9 /PRNewswire-FirstCall/ -- Waters Corporation (NYSE: WAT) announced today that it has shipped the first units of its ground-breaking SYNAPT(TM) G2 Mass Spectrometer, first introduced at the 2009 American Society of Mass Spectrometry (ASMS) annual conference in Philadelphia in June. The instruments are destined for key academic research centers across Europe, North America and Asia and for global pharmaceutical companies and chemical research laboratories. "SYNAPT G2...

2009-12-08 06:00:00

ST. JOSEPH, Mich., Dec. 8 /PRNewswire/ -- GeneGo, Inc., the leading systems biology tools company, announced today that Millipore Corporation has sponsored academic groups from University of Queensland, Sheffield and USC to become members of the collaborative MetaMiner (Stem Cells) project run by GeneGo. MetaMiner is a partnership program for the reconstruction of stem cell pathways and their application in analysis of experimental data as well as knowledge mining. Currently, there are...

2009-12-05 14:32:59

Journal of Biological Chemistry identifies a study conducted at the School of Medicine study as an 'exemplary prototype' Case Western Reserve University researchers, from the School of Medicine's Department of Nutrition, discovered two new metabolic pathways by which products of lipid peroxidation and some drugs of abuse, known as 4-hydroxyacids, are metabolized. The pathways were identified by a combination of metabolomics and mass isotopomer analysis. The findings shed new light on the...

2009-12-01 08:57:00

CAMBRIDGE, Mass., Dec. 1 /PRNewswire/ -- To address the emergence of the synthetic biology industry and to promote its potential, a group of individuals and companies announced the formation of the Synthetic Biology Industry Association (SynBIA) in Cambridge, Massachusetts last week. The goal of the association is to provide a forum for individuals and commercial interests to discuss the new industry, address its opportunities and its challenges, and advocate for its development. Founding...

2009-11-16 13:30:00

BOSTON, Nov. 16 /PRNewswire/ -- Scientists at Biomodels have successfully developed the first model that accurately duplicates human cancer treatment-related fatigue (CTRF). The new model shows, that as in human cancer patients, fatigue is independent of anemia or weight loss and persists long after cancer treatments end. The new model and research findings will be presented today at the American Association for Cancer Research-NCI-EORTC Molecular Targets and Cancer Therapeutics meeting...

2009-11-16 06:00:00

ST. JOSEPH, Mich., Nov. 16 /PRNewswire/ -- GeneGo, Inc., the leading systems biology tools company, announced today the release of a stand alone search product, Eureka! It provides a simple one-button one-window access to GeneGo's manually curated databases. Users can query the database with gene, protein, compound, drug names, diseases, and processes, pathological or toxic categories in a free text format. The results, ranked based on relevance, will present all categories of information...

2009-10-29 06:00:00

ST. JOSEPH, Mich., Oct. 29 /PRNewswire/ -- GeneGo, Inc., the leading systems biology tools company, announced today that they will be launching a new web site with FREE high quality pathway content. On www.genego.com, anyone can now search for genes, proteins, compounds, processes and diseases and access high quality manually curated pathway maps for human, mouse and rat signaling and metabolism. Every step on the pathways is supported by high quality "small experiment" evidence. The web...