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Last updated on April 16, 2014 at 5:23 EDT

Latest T cell Stories

2014-04-14 10:56:31

Manipulating the metabolic process in cells may compensate for defects that can shorten cell life UAlberta researchers are taking a closer look at how two metabolic pathways interact to increase the lifespan of cells with mitochondrial defects. Magnus Friis (PhD ’10) is the lead author of the study, which was published online on April 10 and will be published in the April 24 issue of Cell Reports. Mitochondria produce energy for cells through oxidative metabolism, but the process...

2014-04-11 12:54:50

Too much of a protein called c-FLIPR can trigger autoimmune diseases Apoptosis is used by cells that are changed by disease or are simply not needed any longer to eliminate themselves before they become a hazard to the body—on a cellular level, death is part of life. Disruption of this process can lead to cancer or immunodeficiencies, but also to autoimmune diseases, in which cells attack their own body. HZI scientist Prof Ingo Schmitz and his team investigate the regulation of...

2014-04-01 13:02:44

Antibiotics being explored for the treatment of cystic fibrosis and muscular dystrophy have the potential to trigger autoimmune disease The code for every gene includes a message at the end of it that signals the translation machinery to stop. Some diseases, such as cystic fibrosis and Duchenne muscular dystrophy, can result from mutations that insert this stop signal into the middle of an essential gene, causing the resulting protein to be truncated. Some antibiotics cause the cell's...

2014-03-28 09:26:17

A combination of genetic predisposition and environmental factors is believed to cause autoimmune (type 1) diabetes. A study published on March 27th in PLOS Pathogens gets at the mechanisms by which rotavirus infection contributes to autoimmune diabetes in a mouse model of the disease. NOD (for non-obese diabetic) mice are prone to develop diabetes, and infection with rotavirus accelerates onset of the disease. Barbara Coulson and colleagues, from The University of Melbourne, Australia,...

2014-02-14 16:25:28

Featured Talk Emphasizes Importance of Antigen-Specific Dendritic Cell Cancer Vaccines to Generate Powerful T-Cell Response LOS ANGELES, Feb. 14, 2014 /PRNewswire/ -- ImmunoCellular Therapeutics, Ltd. ("ImmunoCellular") (NYSE MKT: IMUC) today announced that the Company's Founder and Chief Scientific Officer, John S. Yu, MD, delivered a presentation highlighting the therapeutic importance of utilizing antigen-specific dendritic cell (DC) cancer vaccines for inducing a potent T-cell...

Researchers Discover How To Change Cell Types By Flipping A Single Switch
2013-12-04 13:05:09

University of California - Santa Barbara With few exceptions, cells don't change type once they have become specialized — a heart cell, for example, won't suddenly become a brain cell. However, new findings by researchers at UC Santa Barbara have identified a method for changing one cell type into another in a process called forced transdifferentiation. Their work appears today in the journal Development. With C. elegans as the animal model, lead author Misty Riddle, a Ph.D. student...

2013-11-26 16:24:38

The blood stem cells that live in bone marrow are at the top of a complex family tree. Such stem cells split and divide down various pathways that ultimately produce red cells, white cells and platelets. These “daughter” cells must be produced at a rate of about one million per second to constantly replenish the body’s blood supply. Researchers have long wondered what allows these stem cells to persist for decades, when their progeny last for days, weeks or months before they need to...

Modern Spy-Like Immune Gene May Have Come From Neanderthals
2013-11-24 06:03:36

Ranjini Raghunath for redOrbit.com - Your Universe Online A team of European researchers has recently discovered a protein molecule that helps the immune system identify threats and invaders. The molecule, a receptor belonging to the human leukocyte antigen (HLA) system, may have been inherited from Neanderthals, they report. HLA receptors help the immune system identify threats by tagging cells as either friendly or foreign. When a protein looks suspicious, immune cells called...

2013-11-04 08:26:00

Data Demonstrate ZFN-dependent CCR5 Modification of Long-lived Central Memory and Stem-like T-cells RICHMOND, Calif., Nov. 4, 2013 /PRNewswire/ -- Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced today the presentation of clinical data from its program to develop a ZFP Therapeutic(®) for HIV/AIDS. The data demonstrate a reduction in the HIV DNA reservoir since receiving SB-728-T in seven of nine HIV-infected subjects on long-term anti-retroviral therapy (ART), despite a median duration of...

2013-10-28 08:29:38

Agreement gives PELOBIOTECH exclusive distribution rights to ColonyGEL(TM) media for colony-forming cell assays and primary human cell products for research applications SEATTLE, Oct. 28, 2013 /PRNewswire/ -- ReachBio LLC (Seattle, WA, USA) announced today that it has signed an agreement with PELOBIOTECH GmbH (Munich, Germany) giving PELOBIOTECH exclusive distribution rights to ReachBio's full product line for the life science research market within Germany, Austria and Switzerland....


Latest T cell Reference Libraries

Thymus
2013-03-04 12:56:08

The thymus gland is an endocrine organ of the immune system located anteriolateral to the trachea and in between the lungs. Its primary function is to build T lymphocytes for the body’s immune system; therefore, it is most important during childhood and puberty, when it reaches its maximum size. After puberty, it will begin to atrophy and shrink in size. Old age generally brings about hypotrophy of the thymus. In children the thymus is grayish-pink in color and in adults it is yellow. On...

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