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Latest T cell Stories

2011-05-18 16:46:46

New technique will give patients a better chance of having a successful bone marrow or organ transplant University of Minnesota Medical School researchers have discovered a method to quickly and exponentially grow regulatory T-cells "“ also known as "suppressor cells." The new process enables replication of the cells by tens of millions in several weeks, a dramatic increase over previous duplication methods. Historically, regulatory T-cells have been difficult to replicate. The new...

2011-04-28 12:02:00

ROCKVILLE, Md., April 28, 2011 /PRNewswire/ -- MacroGenics, Inc., a privately held biotechnology company that develops immunotherapeutics to treat autoimmune disorders, cancer and infectious diseases, today announced the publication in the journal Blood of preclinical data demonstrating potent inhibition of B-cell lymphoma through redirected T lymphocyte-mediated killing, using its bispecific DART(TM) antibody technology. Included in the peer-reviewed article titled, "Application of...

2011-04-11 12:55:36

Johns Hopkins scientists have developed a simplified, cheaper, all-purpose method they say can be used by scientists around the globe to more safely turn blood cells into heart cells. The method is virus-free and produces heart cells that beat with nearly 100 percent efficiency, they claim. "We took the recipe for this process from a complex minestrone to a simple miso soup," says Elias Zambidis, M.D., Ph.D., assistant professor of oncology and pediatrics at the Johns Hopkins Institute for...

2011-03-14 16:18:19

Elevated p21 expression blocks key steps in viral life cycle Elevated levels of p21, a protein best known as a cancer fighter, may be involved in the ability of a few individuals to control HIV infection with their immune system alone. In a paper in the April edition of the Journal of Clinical Investigation, researchers from the Massachusetts General Hospital (MGH) Infectious Disease Division and the Ragon Institute of MGH, MIT and Harvard report that CD4 T cells from HIV controllers, while...

2011-03-07 21:28:26

The immune system is capable of recognizing tumor growth, and naturally mounts an anti-cancer defense. Dendritic cells (DCs) can take up tumor-derived molecules (antigens) and present them to T cells, and those "primed" T cells are then able to recognize and kill tumor cells. In recent years, researchers have attempted to capitalize upon these natural immune responses to develop new therapies- namely, by generating a pool of tumor antigen-pulsed DCs that might be used as vaccines to augment...

2011-02-16 15:34:29

Scientists from the Walter and Eliza Hall Institute have begun to unravel how blood stem cells regenerate themselves, identifying a key gene required for the process. The discovery that the Erg gene is vitally important to blood stem cells' unique ability to self-renew could give scientists new opportunities to use blood stem cells for tissue repair, transplantation and other therapeutic applications. Professor Doug Hilton, Dr Samir Taoudi and colleagues from the institute's Molecular...

2011-01-31 07:00:00

DURHAM, N.C., Jan. 31, 2011 /PRNewswire/ -- Argos Therapeutics announced today that interleukin (IL)-12 secretion can predict the potency of the company's Arcelis(TM) dendritic cell (DC) immunotherapy and can be used as a potency marker in a Phase 3 clinical trial testing the company's lead product, AGS-003, in metastatic renal cell carcinoma (mRCC). In vitro results published in the Journal of Immunotherapy demonstrate that the potency of mature CD40L RNA electroporated DCs correlates...

2011-01-26 21:07:25

Findings published in Science Translational Medicine demonstrate Lycera's compound selectively silences pathogenic cells and arrests graft-versus-host disease Lycera Corporation, a biopharmaceutical company pioneering an innovative approach to developing novel oral medicines to treat autoimmune diseases, today announced positive data from the University of Michigan demonstrating the role of bioenergetics in selectively inhibiting pathogenic lymphocytes while preserving and enhancing the...

2011-01-20 21:56:48

Researchers take a systematic approach to catalog factors that control blood cell development A small pool of stem cells replenishes the human body with about 200 billion new blood cells daily. But the elaborate circuitry that determines if a cell will develop into a T cell, red blood cell, or one of the nine or more other blood cell types remains largely unknown. A research team led by scientists from the Broad Institute and Brigham and Women's Hospital has taken a systematic approach to...

2011-01-05 13:36:45

Walter and Eliza Hall Institute researchers have discovered how a key viral gene helps viruses evade early detection by the immune system. Their finding is providing new insights into how viruses are able to establish chronic infections, leading scientists to reevaluate their approaches to viral vaccine development. Researchers from the institute's Immunology division together with collaborators at the University of Cambridge (UK) have been studying how the immune system responds to viruses...


Latest T cell Reference Libraries

Thymus
2013-03-04 12:56:08

The thymus gland is an endocrine organ of the immune system located anteriolateral to the trachea and in between the lungs. Its primary function is to build T lymphocytes for the body’s immune system; therefore, it is most important during childhood and puberty, when it reaches its maximum size. After puberty, it will begin to atrophy and shrink in size. Old age generally brings about hypotrophy of the thymus. In children the thymus is grayish-pink in color and in adults it is yellow. On...

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Word of the Day
tesla
  • The unit of magnetic flux density in the International System of Units, equal to the magnitude of the magnetic field vector necessary to produce a force of one newton on a charge of one coulomb moving perpendicular to the direction of the magnetic field vector with a velocity of one meter per second. It is equivalent to one weber per square meter.
This word is named for Nikola Tesla, the inventor, engineer, and futurist.