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Latest T cell Stories

2012-12-19 11:28:22

Researchers at the University of California, San Diego School of Medicine report that tumor cells use stress signals to subvert responding immune cells, exploiting them to actually boost conditions beneficial to cancer growth. The findings are published in the December 18 online issue of the journal PLOS ONE. Lead author Navin R. Mahadevan, a graduate student in the Laboratory of Immunology at the UC San Diego Moores Cancer Center, and colleagues found that tumor cells manipulate a...

2012-11-19 12:34:05

NIH-funded scientists develop new treatment to combat autoimmune disease in mouse model In a mouse model of multiple sclerosis (MS), researchers funded by the National Institutes of Health have developed innovative technology to selectively inhibit the part of the immune system responsible for attacking myelin–the insulating material that encases nerve fibers and facilitates electrical communication between brain cells. Autoimmune disorders occur when T-cells–a type of white...

2012-11-01 23:13:59

Notch — the protein that can help determine cell fate — maintains a stable population of basal cells in the prostate through a positive feedback loop system with another key protein — TGF beta (transforming growth factor beta), said Baylor College of Medicine researchers in the journal Cell Stem Cell. "When basal cell homeostasis (or maintenance of a stable population) is disrupted, it may be part of the process that initiates prostate cancer," said Dr. Li Xin, assistant...

2012-09-24 22:22:57

Kansas State University researchers have discovered a molecule that may be capable of delivering drugs inside the body to treat diseases. For the first time, researchers have designed and created a membrane-bounded vesicle formed entirely of peptides -- molecules made up of amino acids, the building blocks of protein. The membrane could serve as a new drug delivery system to safely treat cancer and neurodegenerative diseases. A study led by John Tomich, professor of biochemistry at...

2012-09-07 09:46:58

Scientists at Washington University School of Medicine in St. Louis have identified a protein essential to repairing the intestine's inner lining. That lining is among the body's busiest highways, trod not only by the food we ingest but also by trillions of microorganisms that aid digestion. Because the intestine plays key roles in absorbing nutrients and containing the microbes, any damage must be fixed promptly. The researchers report Sept. 6 in Science Express that a protein called...

2012-08-23 01:17:34

Johns Hopkins scientists have developed a reliable method to turn the clock back on blood cells, restoring them to a primitive stem cell state from which they can then develop into any other type of cell in the body. The work, described in the Aug. 8 issue of the journal Public Library of Science (PLoS), is "Chapter Two" in an ongoing effort to efficiently and consistently convert adult blood cells into stem cells that are highly qualified for clinical and research use in place of human...

2012-07-16 11:14:56

1. Scientists at A*STAR´s Singapore Immunology Network (SIgN), in collaboration with Newcastle University, UK, the Singapore Institute of Clinical Sciences and clinicians from multiple hospitals in Singapore, have identified a new subset of dendritic cells (DCs) in human peripheral tissue which have a critical role in activating our immune response against harmful pathogens. This research will have significant impact on the design of vaccines and other targeted immunotherapies. The...

2012-07-09 10:16:39

A transcription factor called Lyl-1 is necessary for production of the earliest cells that can become T-cells, critical cells born in the thymus that coordinate the immune response to cancer or infections, said a consortium of researchers led by those from Baylor College of Medicine (www.bcm.edu) in a report in the journal Nature Immunology. These earliest progenitors (called early T lineage progenitor cells) are the first cells that can be identified as being on the road to becoming...

2012-07-06 00:00:14

Chronic inflammatory conditions are extremely common diseases in humans and in the entire animal kingdom. Both in autoimmune diseases and pathogen-caused diseases, the inflamed areas are rapidly colonized by antibody producing B lymphocytes — which organize themselves in highly structured areas called "lymphoid follicles". The scaffold of such follicles is provided by follicular dendritic cells (FDCs). FDCs have important roles in the development of immune responses, since they trap...

2012-06-11 19:02:49

The findings of a new study in monkeys may help clarify why some people infected with HIV are better able to control the virus. They also may pinpoint a target for treatment during early HIV infection aimed at increasing the supply of certain immune cells in the gut, which the study shows could be an important factor in limiting HIV growth in cells throughout the body. The study was led by researchers at the University of California, San Francisco (UCSF) and included Kristina Abel, PhD, an...


Latest T cell Reference Libraries

Thymus
2013-03-04 12:56:08

The thymus gland is an endocrine organ of the immune system located anteriolateral to the trachea and in between the lungs. Its primary function is to build T lymphocytes for the body’s immune system; therefore, it is most important during childhood and puberty, when it reaches its maximum size. After puberty, it will begin to atrophy and shrink in size. Old age generally brings about hypotrophy of the thymus. In children the thymus is grayish-pink in color and in adults it is yellow. On...

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Word of the Day
bibliopole
  • A bookseller; now, especially, a dealer in rare and curious books.
This word comes from a Greek phrase meaning 'book seller.'
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