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Latest T cell Stories

2012-04-16 22:25:08

Inhibiting 2 related enzymes significantly improves survival in mouse model of the disease Columbia University Medical Center (CUMC) scientists have demonstrated that two related enzymes – phosphoinositide-3 kinase (PI3K) gamma and delta – play a key role in the development of T-cell acute lymphoblastic leukemia (T-ALL), a highly aggressive childhood leukemia that is difficult to treat. The study also showed that a dual PI3K gamma/delta inhibitor can significantly prolong...

2012-04-12 11:13:12

Researchers at the University of Liverpool have resolved the debate over the mechanisms involved in the shut-down process during cell division in the body. Research findings, published in the journal PNAS, may contribute to future studies on how scientists could manipulate this shut-down process to ensure that viruses and other pathogens do not enter the cells of the body and cause harm. Previous research has shown that when cells divide, they cannot perform any other task apart from...

2012-04-10 13:53:32

New method for direct identification of antigens The immune system is a vital part of our defenses against pathogens, but it can also attack host tissues, resulting in autoimmune disease. The antigens that induce destructive immune reactions can now be identified directly — without any prior knowledge of their possible structure. Molecules that activate immune responses, generically termed antigens, are recognized by circulating immune cells. In the case of autoimmune reactions,...

2012-03-26 11:05:03

Finding may help develop new treatments for infectious diseases, cancer UCLA researchers pinpointed a new mechanism that potently activates T-cells, the group of white blood cells that play a major role in fighting infections. Published March 25 online in Nature Medicine, the team specifically studied how dendritic cells, immune cells located at the site of infection, become more specialized to fight the leprosy pathogen known as Mycobacterium leprae. Dendritic cells, like scouts in the...

2012-03-14 20:48:18

Researchers identify 190 genes crucial to the function of TLR7 and TLR9, cellular sensors that recognize pathogens and trigger immune responses -- providing insights that could be exploited to develop new therapies for infectious and autoimmune diseases In a healthy immune system, invading pathogens trigger a cascade of alerts and responses to fight off the infection. Sensors called toll-like receptors, or TLRs, act as one of the first lines of defense. Two of these sensors, known as TLR7...

2012-03-14 20:46:55

Researchers at the RIKEN Omics Science Center (OSC) have successfully developed and demonstrated a new experimental technique for producing cells with specific functions through the artificial reconstruction of transcriptional regulatory networks. As an alternative to induced pluripotent stem cells, the technique promises to enable faster and more efficient production of functional cells for use in cancer therapy and a variety of other areas. Starting with the first-ever production of...

2012-03-14 12:46:43

Since the mid-1990s, doctors have had the protein Mer in their sights — it coats the outside of cancer cells, transmitting signals inside the cells that aid their uncontrolled growth. A University of Colorado Cancer Center study, recently published in the journal PLoS ONE, found another home for Mer — inside cancer cells´ nuclei — and perhaps another role for this protein that can point the way to novel, targeted treatments. “We´ve known that leukemic B...

2012-03-02 14:20:19

Upon fertilisation, a single cell is formed when egg and sperm fuse. Our entire body, with more than 200 specialised cell types and billions of cells are formed from this single cell. It is a scientific mystery how the early stem cells know what cell type to become, but a precise timing of the process is crucial for correct development and function of our body. Researchers across the world chase knowledge about our stem cells, as this knowledge holds great promises for development of...

2012-02-24 18:00:05

Cells that die naturally generate a lot of internal debris that can trigger the immune system to attack the body, leading to diseases such as lupus. Now Georgia Health Sciences University researchers report that an enzyme known to help keep a woman's immune system from attacking a fetus also helps block development of these autoimmune diseases that target healthy tissues, such as DNA or joints. The findings point toward new treatment strategies for autoimmune diseases, which are on the...


Latest T cell Reference Libraries

Thymus
2013-03-04 12:56:08

The thymus gland is an endocrine organ of the immune system located anteriolateral to the trachea and in between the lungs. Its primary function is to build T lymphocytes for the body’s immune system; therefore, it is most important during childhood and puberty, when it reaches its maximum size. After puberty, it will begin to atrophy and shrink in size. Old age generally brings about hypotrophy of the thymus. In children the thymus is grayish-pink in color and in adults it is yellow. On...

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Word of the Day
reremouse
  • A bat.
The word 'reremouse' comes from Middle English reremous, from Old English hrēremūs, hrērmūs ("bat"), equivalent to rear (“to move, shake, stir”) +‎ mouse.
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