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Latest T cell Stories

2011-12-12 22:28:15

Multicellular organisms must have a means for cells to communicate with one another. Past research has shown that plants possess the ability to directly transfer materials between adjacent cells, through holes in their cell walls called plasmodesmata (PD). Now, a study published by Cell Press in the December issue of the journal Developmental Cell reveals one way to control the size of these PD channels, to prevent or allow the passage of important signals between cells, during plant...

2011-12-09 11:51:09

A protein called enhanced disease susceptibility 1 (EDS1) plays a central role in plants' ability to defend themselves from pathogens. But in the almost two decades since it was discovered, how EDS1 works at the molecular level has been a mystery. Solving the mystery will help scientists enhance disease resistance in crops. Two papers published in the Dec. 9 issue of Science (http://www.sciencemag.org/magazine) demonstrate how EDS1 activates different components of the plant immune system,...

Changes In Bioelectric Signals Cause Tadpoles To Grow Eyes In Back, Tail
2011-12-09 03:55:59

For the first time, scientists have altered natural bioelectrical communication among cells to directly specify the type of new organ to be created at a particular location within a vertebrate organism. Using genetic manipulation of membrane voltage in Xenopus (frog) embryos, biologists at Tufts University's School of Arts and Sciences were able to cause tadpoles to grow eyes outside of the head area. The researchers achieved most surprising results when they manipulated membrane voltage...

2011-12-08 13:39:57

FINDINGS: A long non-coding RNA (lncRNA) prevents programmed cell death during one of the final stages of red blood cell differentiation, according to Whitehead Institute researchers. This is the first time a lncRNA has been found to play a role in red blood cell development and the first time a lncRNA has been shown to affect programmed cell death. RELEVANCE: Programmed cell death, or apoptosis, occurs in many cell development pathways; preventing normal cell death is a key step in the...

Cell Cultures From A Machine
2011-10-28 11:01:58

Cell cultures form the basis of day-to-day research work in applications that range from the development of drugs and vaccines to the decoding of functions of individual genes. Up until now, cell cultures have been sown, tended, observed and transferred to vessels — all by hand. A new device automates these worksteps completely. The human genome has been decoded. Of all the puzzles it contains, though, many remain unsolved. We know that the genome provides the blueprint for various...

2011-10-27 15:37:17

FINDINGS: Whitehead Institute scientists have determined that master transcription factors determine the genes regulated by key signaling pathways. In this way, signaling pathways are targeted to genes that are most relevant to each cell type and tailor gene expression to control cell state, growth, differentiation, and death. RELEVANCE: When signaling pathways operate properly, a cell receives instructions from its neighbors and the environment that tweak gene expression and control the...

2011-10-21 13:47:10

Exceptional cognitive and physical function in old age leaves a tell-tale immunologic fingerprint, say researchers at the University of Pittsburgh and Children's Hospital of Pittsburgh of UPMC. Likewise, older adults who have mild impairments bear a distinct immunologic pattern, too, according to findings published today in the Public Library of Science: One. Old age is not synonymous with impairment and disability, noted lead investigator Abbe N. de Vallejo, Ph.D., associate professor of...

2011-10-03 19:57:29

Discovery could lead to new and better vaccines for Listeria, HIV and other pathogens Researchers at the La Jolla Institute for Allergy & Immunology have identified a previously unknown mechanism that generates protective immune memory cells to fight recurring infections at the body's mucosal linings — which include the mouth, the intestines, the lungs and other areas. These are the main entry points for many viruses and other infectious organisms. The findings were published...

2011-10-03 12:30:51

A central element of the immune system has remained constant through more than 400 million years of evolution, according to new research at National Jewish Health. In the September 29, 2011, online version of the journal Immunity, the researchers report that T-cell receptors from mice continue to function even when pieces of shark, frog and trout receptors are substituted in. The function of the chimeric receptors depends on a few crucial amino acids, found also in humans, that help the...


Latest T cell Reference Libraries

Thymus
2013-03-04 12:56:08

The thymus gland is an endocrine organ of the immune system located anteriolateral to the trachea and in between the lungs. Its primary function is to build T lymphocytes for the body’s immune system; therefore, it is most important during childhood and puberty, when it reaches its maximum size. After puberty, it will begin to atrophy and shrink in size. Old age generally brings about hypotrophy of the thymus. In children the thymus is grayish-pink in color and in adults it is yellow. On...

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Word of the Day
drawcansir
  • A blustering, bullying fellow; a pot-valiant braggart; a bully.
This word is named for Draw-Can-Sir, a character in George Villiers' 17th century play The Rehearsal.
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