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Latest T cell Stories

2011-10-27 15:37:17

FINDINGS: Whitehead Institute scientists have determined that master transcription factors determine the genes regulated by key signaling pathways. In this way, signaling pathways are targeted to genes that are most relevant to each cell type and tailor gene expression to control cell state, growth, differentiation, and death. RELEVANCE: When signaling pathways operate properly, a cell receives instructions from its neighbors and the environment that tweak gene expression and control the...

2011-10-21 13:47:10

Exceptional cognitive and physical function in old age leaves a tell-tale immunologic fingerprint, say researchers at the University of Pittsburgh and Children's Hospital of Pittsburgh of UPMC. Likewise, older adults who have mild impairments bear a distinct immunologic pattern, too, according to findings published today in the Public Library of Science: One. Old age is not synonymous with impairment and disability, noted lead investigator Abbe N. de Vallejo, Ph.D., associate professor of...

2011-10-03 19:57:29

Discovery could lead to new and better vaccines for Listeria, HIV and other pathogens Researchers at the La Jolla Institute for Allergy & Immunology have identified a previously unknown mechanism that generates protective immune memory cells to fight recurring infections at the body's mucosal linings — which include the mouth, the intestines, the lungs and other areas. These are the main entry points for many viruses and other infectious organisms. The findings were published...

2011-10-03 12:30:51

A central element of the immune system has remained constant through more than 400 million years of evolution, according to new research at National Jewish Health. In the September 29, 2011, online version of the journal Immunity, the researchers report that T-cell receptors from mice continue to function even when pieces of shark, frog and trout receptors are substituted in. The function of the chimeric receptors depends on a few crucial amino acids, found also in humans, that help the...

2011-09-22 06:17:38

(Ivanhoe Newswire) -- Stanford researchers have created the first human heart cells that can be paced with light, providing new insight into the heart's function. To create the light-responsive heart cells, the investigators first inserted DNA encoding a light-sensitive protein -- known as ChR2 -- into human embryonic stem cells. ChR2 controls the flow of electrically-charged ions into the cell. The primary ion for heart cells is sodium, which initiates the electrochemical cascade that...

2011-09-19 23:34:43

Our livers can fight back against the immune system–reducing organ rejection but also making us more susceptible to liver disease. Scientists at the Centenary Institute in Sydney have seen for the first time (in mice) how the liver goes independent, engulfing and destroying the body's defence troops–T-cells. Their discovery, published overnight in PNAS (Proceedings of the National Academy of Sciences), opens the way to both new approaches to transplant rejection, and to the...

Image 1 - Biochemical Cell Signals Quantified For The First Time
2011-09-18 06:16:17

  Just as cell phones and computers transmit data through electronic networks, the cells of your body send and receive chemical messages through molecular pathways. The term “cell signaling” was coined more than 30 years ago to describe this process. Now, for the first time, scientists have quantified the data capacity of a biochemical signaling pathway and found a surprise — it´s way lower than even an old-fashioned, dial-up modem. “This key...

When It Comes To Speaking Out, Cells Wait Their Turn
2011-09-06 06:56:37

  Revealing how cells communicate, Tel Aviv University research could lead to new cancer drugs and more Cell communication is essential for the development of any organism. Scientists know that cells have the power to "talk" to one another, sending signals through their membranes in order to "discuss" what kind of cell they will ultimately become – whether a neuron or a hair, bone, or muscle. And because cells continuously multiply, it's easy to imagine a cacophony of...

2011-08-25 21:34:14

Study finds KN1 trafficking through tiny channels called plasmodesmata cannot occur without chaperonins Like all living things, plants depend for their growth and sustenance on elaborate signaling networks to maintain stem cells, cells that have an almost magical regenerative capacity. The signals sent through these networks convey an incredible diversity of instructions, which make it possible for plants to follow genetic and cellular programs regulating growth, shape, and energy...

2011-08-05 12:57:44

Innate memory provides protection against vaccinia Researchers have demonstrated that cells of the innate immune system are capable of "memory", and of mounting rapid protection to an otherwise lethal dose of live vaccinia virus. The study, published in the Open Access journal PLoS Pathogens on August 4th, challenges previous thought that only B cells and T cells can store memory to ward off future infection. The finding, by researchers from Beth Israel Deaconess Medical Center, Harvard...


Latest T cell Reference Libraries

Thymus
2013-03-04 12:56:08

The thymus gland is an endocrine organ of the immune system located anteriolateral to the trachea and in between the lungs. Its primary function is to build T lymphocytes for the body’s immune system; therefore, it is most important during childhood and puberty, when it reaches its maximum size. After puberty, it will begin to atrophy and shrink in size. Old age generally brings about hypotrophy of the thymus. In children the thymus is grayish-pink in color and in adults it is yellow. On...

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Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'