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Latest T helper 17 cell Stories

2014-02-28 13:39:01

Study helps explain chronic inflammation in autoimmunity and cancer Activation of beta-catenin, the primary mediator of the ubiquitous Wnt signaling pathway, alters the immune system in lasting and harmful ways, a team of Chicago-based researchers demonstrate in the February 26, 2014, issue of Science Translational Medicine. An increase in beta-catenin in certain types of T cells—a class of white blood cells—causes chronic inflammation in the intestine and colon, eventually leading...

2013-12-11 13:08:56

An experimental compound synthesized and developed by scientists from the Florida campus of The Scripps Research Institute (TSRI) has the capacity to significantly reduce joint inflammation in animal models of rheumatoid arthritis, an autoimmune disease that affects more than two million Americans. The study was published recently online ahead of print by the journal Arthritis & Rheumatism. The study showed the compound, known as SR2211, blocked development of virtually all symptoms...

2013-08-08 23:17:34

MD Biosciences focuses on rapid and cost effective models of psoriasis involving the IL-23/Th17 axis in order to provide companies alternatives to complex and cost prohibitive xenotransplantation models for screening. With the earlier launch of the IMQ model and now the IL-23 psoriasis model, MD Biosciences offers a range of rapid models for dermal conditions such as dermatitis and psoriasis. St Paul, MN (PRWEB) August 08, 2013 Recent psoriasis research has focused extensively on the...

Autoimmune Diseases Driven By Excessive Intake Of Dietary Salt
2013-03-07 11:01:00

Alan McStravick for redOrbit.com - Your Universe Online Over the previous several years, medical professionals have noted and documented marked increases in the prevalence of autoimmune diseases. An international team of scientists and researchers have come together in an attempt to identify the cause behind the increase in diseases like multiple sclerosis, rheumatoid arthritis, psoriasis and other diseases. What they have learned is that there is a connection between dietary salt intake...

2012-07-09 10:10:10

Researchers from Brigham and Women's Hospital (BWH) have made a groundbreaking discovery that will shape the future of melanoma therapy. The team, led by Thomas S. Kupper, MD, chair of the BWH Department of Dermatology, and Rahul Purwar, PhD, found that high expression of a cell-signaling molecule, known as interleukin-9, in immune cells inhibits melanoma growth. Their findings will be published online in the July 8, 2012 issue of Nature Medicine. After observing mice without genes...

2011-12-23 08:29:17

Vaccines with broader reach might be made by stimulating specialized immune cells to recognize foreign cell membrane proteins that are shared across bacterial species, say researchers from Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine in a report published online today in Immunity. The approach could be particularly beneficial in preventing infection by multi-drug resistant organisms. The genetic heritage of organisms such as oysters, frogs...

2011-10-11 12:13:17

An estimated 1.3 million people in the United States suffer from rheumatoid arthritis. The causes behind this chronic disease – which can exhibit itself as pain, swelling, stiffness, deformation, and loss of function in the joints – have eluded scientists for centuries. A new study by UNC researchers offers tantalizing glimmers about the roles of a gene called CCR2, an immune system cell called Th17 cell, and a missing monocyte. The study contributes to a better understanding...

2011-08-10 22:35:14

Discovery has implications for autoimmune diseases, HIV infection and possibly in cancer as a biomarker and in the development of new treatments New research led by Derya Unutmaz, MD associate professor, the Departments of Pathology, Medicine, and Microbiology at NYU School of Medicine and Mark Sundrud, PhD, of Tempero Pharmaceuticals, Inc., has identified a novel sensory pathway that modulates the potency of Th17 cell responses. The new research is highlighted in the August 8th online...

2011-07-27 06:14:00

SAN DIEGO, July 27, 2011 /PRNewswire/ -- Visionary Pharmaceuticals, Inc., announced today that the company has raised seed round investments from a consortium of Angel Investors. The company is using the capital to develop novel small molecule retinoic acid related orphan receptor (ROR) modulators targeting TH17 T-lymphocytes for the treatment of various autoimmune disorders including rheumatoid arthritis, multiple sclerosis, psoriasis and COPD. Visionary Pharmaceuticals has created...

2011-07-22 14:50:09

St. Jude Children's Research Hospital scientists show that the molecule serves as a bridge between the two arms of the immune system that provides a new mechanism guiding T cell differentiation St. Jude Children's Research Hospital investigators have identified a signaling molecule that functions like a factory supervisor to ensure that the right mix of specialized T cells is available to fight infections and guard against autoimmune disease. The research also showed the molecule, phosphatase...


Word of the Day
mundungus
  • A stinking tobacco.
  • Offal; waste animal product; organic matter unfit for consumption.
This word comes from the Spanish 'mondongo,' tripe, entrails.