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Latest T helper cell Stories

2013-12-16 23:01:48

St. Jude Children’s Research Hospital scientists find mechanism that launches production of the specialized T cells essential for combating infectious agents and that offers new therapeutic possibilities Memphis, Tenn. (PRWEB) December 16, 2013 St. Jude Children’s Research Hospital scientists have identified a protein complex that is essential for jumpstarting the immune response during the critical first 24 hours of an infection. The research appears in the current issue of the...

2013-10-02 12:46:56

In many ways, the spread of HIV has been fueled by substance abuse. Shared needles and drug users' high-risk sexual behaviors are just some of the ways that narcotics such as cocaine have played a key role in the AIDS epidemic in much of the world. There is, however, relatively little research into how drugs can impact the body's defenses against the virus. But a new UCLA study published in the October issue of the Journal of Leukocyte Biology examines how cocaine affects a unique...

2013-09-30 15:48:15

New research published in the Journal of Leukocyte Biology suggests that cocaine makes quiescent CD4 T cells susceptible to HIV resulting in significant infection and new virus production Cocaine use may increase one's vulnerability to HIV infection, according to a new research report published in the Journal of Leukocyte Biology. In the report, scientists show that cocaine alters immune cells, called "quiescent CD4 T cells," to render them more susceptible to the virus, and at the same...

2013-08-27 12:35:20

HIV-infected people who carry a gene for a specific protein face a 20-fold greater risk of contracting cryptococcal disease, according to a study published in mBio®, the online open-access journal of the American Society for Microbiology. Cryptococcus neoformans is the most common cause of fungal meningitis among HIV-infected individuals. While the disease is a risk for everyone with HIV who has a very low level of CD4+ T cells, researchers have discovered that those with the gene for the...

2013-08-08 11:03:27

Implications for development of immune system and allergies, say researchers The range of helpful bacteria in the guts of infants delivered by caesarean section, during their first two years of life, is narrower than that of infants delivered vaginally, indicates a small study published online in the journal Gut. This has implications for the development of the immune system, say the researchers, particularly as the C-section infants had lower levels of the major group of gut bacteria...

2013-08-04 12:20:16

St. Jude Children's Research Hospital researchers discover how to unleash the immune system against cancer in mice without triggering autoimmune reactions MEMPHIS, Tenn., August 4, 2013 /PRNewswire-USNewswire/ -- St. Jude Children's Research Hospital scientists have discovered a way to target the immune system to shrink or eliminate tumors in mice without causing autoimmune problems. Researchers also found evidence that the same mechanism may operate in humans. The study was...

2013-07-19 10:56:35

Biologists at the California Institute of Technology (Caltech) have worked out the details of a mechanism that leads undifferentiated blood stem cells to become macrophages—immune cells that attack bacteria and other foreign pathogens. The process involves an unexpected cycle in which cell division slows, leading to an increased accumulation of a particular regulatory protein that in turn slows cell division further. The finding provides new insight into how stem cells are...

2013-07-17 11:07:59

1. Scientists at A*STAR’s Singapore Immunology Network (SIgN) have discovered a new class of white blood cells in human lung and gut tissues that play a critical role as the first line of defense against harmful fungal and bacterial infections. This research will have significant impact on the design of vaccines and targeted immunotherapies for diseases caused by infectious microbes such as the hospital-acquired pneumonia. 2. The scientists also showed for the first time...

2013-07-08 08:28:08

Conference to feature recent advances in Generex Oral-lyn(TM) development and planned broadening of the Generex Diabetes Program WORCESTER, Mass. and TORONTO, July 8, 2013 /PRNewswire/ -- Generex Biotechnology Corporation (www.generex.com) (OTCBB: GNBT) today announced that it will be hosting a conference call featuring members of its Generex Oral-lyn(TM) and Diabetes Program Team. The conference call will focus on recent developments in the global Generex Oral-lyn(TM) buccal...

2013-05-24 11:36:05

Scientists at Emory Vaccine Center have shown that an immune regulatory molecule called IL-21 is needed for long-lasting antibody responses in mice against viral infections. The results are published in the Journal of Virology. "Our findings highlight how IL-21 could be important in the development of antiviral vaccines," says research associate Ata Ur Rasheed Mohammed, PhD, the first author of the paper. The senior author is Rafi Ahmed, PhD, director of the Emory Vaccine Center and a...