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Last updated on April 23, 2014 at 10:44 EDT

Latest T helper cell Stories

2012-07-25 09:31:19

Researchers: Findings about innate peptide may offer new avenue of research for combating HIV, other viruses Human defensins, aptly named antimicrobial peptides, are made in immune system cells and epithelial cells (such as skin cells and cells that line the gut). One of these peptides, human neutrophil peptide 1, under certain circumstances hinders HIV infection, but exactly how it works remains unclear. HIV entry into mature T-helper cells (cells essential to the immune system)...

2012-07-16 13:59:04

Inefficient helper T cell response might explain why some patients relapse after clearing the infection Helper cells traditionally thought to only assist killer white blood cells may be the frontline warriors when battling hepatitis A infection. These are the findings from a Nationwide Children´s Hospital study appearing in a recent issue of the Journal of Experimental Medicine. Hepatitis A is a highly contagious liver infection caused by the hepatitis A virus. Despite the...

2012-07-09 10:10:10

Researchers from Brigham and Women's Hospital (BWH) have made a groundbreaking discovery that will shape the future of melanoma therapy. The team, led by Thomas S. Kupper, MD, chair of the BWH Department of Dermatology, and Rahul Purwar, PhD, found that high expression of a cell-signaling molecule, known as interleukin-9, in immune cells inhibits melanoma growth. Their findings will be published online in the July 8, 2012 issue of Nature Medicine. After observing mice without genes...

2012-07-05 10:35:24

Reprogramming asthma-promoting immune cells in mice diminishes airway damage and inflammation, and could potentially lead to new treatments for people with asthma, researchers have found. The researchers were able to reprogram the asthma-promoting cells (called Th2 (T-helper 2) cells) after identifying an enzyme that modifies the DNA of these cells. The enzyme could be a target for the development of new treatments for chronic inflammatory diseases, in particular allergic asthma, caused by...

2012-06-11 19:02:49

The findings of a new study in monkeys may help clarify why some people infected with HIV are better able to control the virus. They also may pinpoint a target for treatment during early HIV infection aimed at increasing the supply of certain immune cells in the gut, which the study shows could be an important factor in limiting HIV growth in cells throughout the body. The study was led by researchers at the University of California, San Francisco (UCSF) and included Kristina Abel, PhD, an...

2012-06-06 06:25:46

WORCESTER, Mass. and TORONTO, June 6, 2012 /PRNewswire/ -- Generex Biotechnology Corporation (OTCBB: GNBT.OB) announced today a podium presentation on the technology and clinical results from the on-going Phase II clinical trial of the AE37 breast cancer vaccine being developed by Generex wholly-owned subsidiary Antigen Express, Inc. The presentation was at the Annual Meeting of the American Society of Clinical Oncology (ASCO) (http://chicago2012.asco.org) on June 4, 2012 in Chicago, IL....

2012-06-05 06:28:19

WORCESTER, Mass. and TORONTO, June 5, 2012 /PRNewswire/ -- Generex Biotechnology Corporation (OTCBB: GNBT.OB) announced today that new immune response data from the on-going Phase II clinical trial of the AE37 breast cancer vaccine undertaken by Generex wholly-owned subsidiary Antigen Express, Inc. was presented at the Annual Meeting of the American Society of Clinical Oncology (ASCO) (http://chicago2012.asco.org) on June 2, 2012 in Chicago, IL. The abstract entitled: 'An assessment of...

2012-05-31 11:52:07

After being infected with SIV, rhesus macaques that had more of a certain type of immune cell in their gut than others had much lower levels of the virus in their blood, and for 6 months after infection were better able to control the virus After being infected with simian immunodeficiency virus (SIV) in a laboratory study, rhesus macaques that had more of a certain type of immune cell in their gut than others had much lower levels of the virus in their blood, and for six months after...

2012-05-22 02:05:56

University of Cincinnati (UC) researchers have found that an imbalance in the regulation of certain T cells–the cells in the body that fight off infection or attack the system in certain autoimmune diseases–may put certain people at a higher risk of having recurrent cases of Clostridium difficile, or C. Diff, infection. These findings are being presented via poster during Digestive Disease Week, Monday, May 21, 2012, in San Diego. C. difficile is a bacterium that can be...

2012-05-08 09:45:39

Scientists at The Scripps Research Institute have made an important discovery about the internal programming of B cells, the immune cells that make antibodies against infections. The finding opens the way for the development of vaccines that can work more efficiently and hints at therapies for conditions in which B cells cause harm–such as the autoimmune disease lupus erythymatosus, severe allergies, and B-cell lymphomas. The discovery reveals that B cells produce special proteins to...