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Latest T helper cell Stories

2012-09-12 00:57:17

Novel method could help advance the fight against persistent 'HIV latency' Scientists at the Gladstone Institutes have gotten us one step closer to understanding and overcoming one of the least-understood mechanisms of HIV infection–by devising a method to precisely track the life cycle of individual cells infected with HIV, the virus that causes AIDS. In a paper being published online today in Lab on a Chip, the laboratory of Gladstone Investigator Leor Weinberger, PhD, announced...

Interactions Between Malaria Parasite and HIV Demonstrated With Novel Technique
2012-08-16 08:19:05

The World Health Organization estimates that in 2011 there were 216 million cases of malaria and 34.2 million people living with HIV. These diseases particularly afflict sub-Saharan Africa, where large incidence of co-infection result in high mortality rates. Yet, in spite of this global pandemic, interactions between the parasite that causes malaria, Plasmodium falciparum, and HIV-1 are poorly understood. However, a new video article in JoVE, the Journal of Visualized Experiments, that...

2012-08-15 01:02:20

Researcher finds autoimmune response contributes to inflammation in the artery wall Most people probably know that heart disease remains the nation's No. 1 killer. But what many may be surprised to learn is that cholesterol has a major accomplice in causing dangerous arterial plaque buildup that can trigger a heart attack. The culprit? Inflammatory cells produced by the immune system. A number of research studies have demonstrated inflammation's role in fueling plaque buildup, also...

2012-07-30 12:57:20

Findings may affect how doctors treat allergic inflammation and organ transplant rejection A research team led by Xian Chang Li, MD, PhD, Brigham and Women's Hospital (BWH) Transplantation Research Center, has shed light on how a population of lymphocytes, called CD4+ T cells, mature into various subsets of adult T helper cells. In particular, the team uncovered that a particular cell surface molecule, known as OX40, is a powerful inducer of new T helper cells that make copious amounts of...

2012-07-25 09:31:19

Researchers: Findings about innate peptide may offer new avenue of research for combating HIV, other viruses Human defensins, aptly named antimicrobial peptides, are made in immune system cells and epithelial cells (such as skin cells and cells that line the gut). One of these peptides, human neutrophil peptide 1, under certain circumstances hinders HIV infection, but exactly how it works remains unclear. HIV entry into mature T-helper cells (cells essential to the immune system)...

2012-07-16 13:59:04

Inefficient helper T cell response might explain why some patients relapse after clearing the infection Helper cells traditionally thought to only assist killer white blood cells may be the frontline warriors when battling hepatitis A infection. These are the findings from a Nationwide Children´s Hospital study appearing in a recent issue of the Journal of Experimental Medicine. Hepatitis A is a highly contagious liver infection caused by the hepatitis A virus. Despite the...

2012-07-09 10:10:10

Researchers from Brigham and Women's Hospital (BWH) have made a groundbreaking discovery that will shape the future of melanoma therapy. The team, led by Thomas S. Kupper, MD, chair of the BWH Department of Dermatology, and Rahul Purwar, PhD, found that high expression of a cell-signaling molecule, known as interleukin-9, in immune cells inhibits melanoma growth. Their findings will be published online in the July 8, 2012 issue of Nature Medicine. After observing mice without genes...

2012-07-05 10:35:24

Reprogramming asthma-promoting immune cells in mice diminishes airway damage and inflammation, and could potentially lead to new treatments for people with asthma, researchers have found. The researchers were able to reprogram the asthma-promoting cells (called Th2 (T-helper 2) cells) after identifying an enzyme that modifies the DNA of these cells. The enzyme could be a target for the development of new treatments for chronic inflammatory diseases, in particular allergic asthma, caused by...


Word of the Day
jument
  • A beast of burden; also, a beast in general.
'Jument' ultimately comes from the Latin 'jugum,' yoke.
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