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Latest T helper cell Stories

2012-01-03 13:45:30

New research published in the Journal of Leukocyte Biology suggests that high levels of estradiol present prior to ovulation decreases immune system effectiveness resulting in growth and promotion of infection A new research report in the Journal of Leukocyte Biology (http://www.jleukbio.org) suggests that a woman's ovarian cycle plays an important role in her susceptibility to infection. Specifically, researchers from Spain and Austria found that women are most susceptible to infection,...

2011-12-23 08:29:17

Vaccines with broader reach might be made by stimulating specialized immune cells to recognize foreign cell membrane proteins that are shared across bacterial species, say researchers from Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine in a report published online today in Immunity. The approach could be particularly beneficial in preventing infection by multi-drug resistant organisms. The genetic heritage of organisms such as oysters, frogs...

2011-12-21 13:06:29

It is vital that the body's own immune system does not overreact. If its key players, the helper T cells, get out of control, this can lead to autoimmune diseases or allergies. An immune system overreaction against infectious agents may even directly damage organs and tissues. Immune cells called regulatory T cells ("Tregs") ensure that immune responses take place in a coordinated manner: They downregulate the dividing activity of helper T cells and reduce their production of immune...

2011-12-21 08:30:00

WORCESTER, Mass. and TORONTO, Dec. 21, 2011 /PRNewswire/ -- Generex Biotechnology Corporation (OTCBB: GNBT.OB) today announced that the previously announced Bloomberg Television segment on the Antigen Express breast cancer vaccine aired yesterday evening (December 20, 2011). The segment can be viewed on the Company's website at www.generex.com or on the Bloomberg website at http://www.bloomberg.com/video/83137924/. (Logo: http://photos.prnewswire.com/prnh/20110106/NY25057LOGO-b)...

2011-12-20 09:43:00

WORCESTER, Mass. and TORONTO, Dec. 20, 2011 /PRNewswire/ -- Generex Biotechnology Corporation (OTCBB: GNBT.OB) today announced that the Bloomberg Television segment on the Antigen Express breast cancer vaccine did not air yesterday as originally scheduled (and announced in Bloomberg Television's December 16, 2011 promotional spot). The Company will provide a further update once representatives of Bloomberg Television advise as to a rescheduled air date and time. (Logo:...

2011-12-15 17:19:14

Steve Reiner, MD, professor of Medicine, and Burton Barnett, a doctoral student in the Reiner lab at the Perelman School of Medicine at the University of Pennsylvania, have shown how immune cells, called B lymphocytes, are able to produce daughter cells that are not equal, a finding that might explain how lifelong antibodies are made after vaccination. How do immune cells make daughter cells that are different form one another, rather than splitting into identical daughter cells? The...

2011-12-14 19:40:57

Breakthrough offers new hope in fight against global pandemic Scientists at the Gladstone Institutes have discovered new protein fragments in semen that enhance the ability of HIV, the virus that causes AIDS, to infect new cells–a discovery that one day could help curb the global spread of this deadly pathogen. HIV/AIDS has killed more than 25 million people around the world since first being identified some 30 years ago. In the United States alone, more than one million people...

2011-12-14 08:30:00

WORCESTER, Mass. and TORONTO, Dec. 14, 2011 /PRNewswire/ -- Generex Biotechnology Corporation (OTCBB: GNBT.OB) today announced that Bloomberg Television will air a segment on the immunotherapeutic breast cancer vaccine being developed by its wholly-owned subsidiary, Antigen Express, Inc. The story, expected to air December 19, 2011, will cover the Company's novel Ii-Key Hybrid-based HER-2/neu Peptide Vaccine (AE37), which is the subject of an ongoing Phase 2 clinical study in patients with...

2011-12-14 02:28:19

Chronic infections by viruses such as HIV or hepatitis C eventually take hold because they wear the immune system out, a phenomenon immunologists describe as exhaustion. Yet exhausted immune cells can be revived after the introduction of fresh cells that act like coaches giving a pep talk, researchers at Emory Vaccine Center have found. Their findings provide support for an emerging strategy for treating chronic infections: infusing immune cells back into patients after a period of...

2011-12-12 21:51:48

Research describes advantages of new vaccine adjuvant New research from the laboratory of Dr. Elizabeth Leadbetter at the Trudeau Institute may lead to a whole new class of vaccines. Dr. Leadbetter's lab has discovered new properties of a potential vaccine adjuvant that suggest it could be useful for enhancing protection against a number of different infections. This new data will be published in the January 2012 issue of the journal Nature Immunology (Vol. 13, pp. 44-50). The paper, "iNKT...