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Latest T7 DNA Helicase Stories

2011-09-19 07:54:41

With an eye toward understanding DNA replication, Cornell researchers have learned how a helicase enzyme works to actually unzip the two strands of DNA. (Nature, online Sept. 18, 2011.) At the heart of many metabolic processes, including DNA replication, are enzymes called helicases. Acting like motors, these proteins travel along one side of double-stranded DNA, prompting the strands to "zip" apart. What had been a mystery was the exact mechanics of this vital biological process...