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Latest Tau protein Stories

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2010-09-17 15:09:03

By Jim Dryden, Washington University in St. Louis An international team of Alzheimer's disease experts, led by Washington University School of Medicine in St. Louis, has uncovered a gene variation that appears to predict the rate at which Alzheimer's disease will progress. The investigators report their findings online in the journal Public Library of Science (PLoS) Genetics. Whereas previous studies have focused on factors that influence the risk for Alzheimer's, the new research points to a...

2010-05-14 10:16:25

Whitehead Institute researchers have determined a key part of how cells regulate the chromosome/microtubule interface, which is central to proper chromosomal distribution during cell division. "This is the surveillance machinery that makes sure that the chromosomes are divided correctly between cells," says Whitehead Member Iain Cheeseman. The findings are published in this week's issue of Molecular Cell. During cell division, the cell's DNA is consolidated into X-shaped chromosome pairs that...

2010-03-01 15:14:02

Uncovers new explanation for the spread of key protein within the brain LOWELL, Mass. "“ A team of researchers at UMass Lowell has found a new mechanism by which a key protein associated with Alzheimer's disease can spread within the human brain. The research, led by UMass Lowell biological sciences professor Garth Hall, gives new hope that the disease may someday be cured. It provides a new explanation of how the protein tau, a normal human protein that becomes toxic in Alzheimer's...

2010-02-25 07:05:00

WASHINGTON, Feb. 25 /PRNewswire/ -- Complementary approaches to Alzheimer's research were recognized as four scientists received the prestigious MetLife Foundation Awards for Medical Research in Alzheimer's Disease in Washington, D.C. during a scientific briefing and luncheon. Todd E. Golde, M.D., Ph.D., professor of neuroscience at the University of Florida and director of its Center for Translational Research in Neurodegenerative Diseases, and Edward H. Koo, M.D., professor of...

2010-01-17 08:25:00

Nearly 20 years ago Huntington Potter kicked up a storm of controversy with the idea that Down syndrome and Alzheimer's were the same disease. Now the evidence is in: He was right. And that's not all. Down syndrome, artery-clogging cardiovascular disease, and possibly even diabetes, appear to share a common disease mechanism with Alzheimer's disease, Dr. Potter and colleagues at the Florida Alzheimer's Disease Research Center, USF Health Byrd Alzheimer's Institute, recently reported. The...

2010-01-15 17:50:53

TGen-led team finds 3 proteins that dismantle 'bridges' within brain cells A scientific group led by the Translational Genomics Research Institute (TGen) have identified three kinases, or proteins, that dismantle connections within brain cells, which may lead to memory loss associated with Alzheimer's disease. These findings, the results of a multi-year TGen study, are published in this month's edition of BMC Genomics in a paper titled: High-content siRNA screening of the kinome identifies...

2009-11-11 18:05:06

Protein reduces levels of amyloid beta and tau hyperphosphorylation, 2 hallmarks of Alzheimer's Investigators at Burnham Institute for Medical Research (Burnham) and colleagues have identified a novel mouse gene (Rps23r1) that reduces the accumulation of two toxic proteins that are major players in Alzheimer's disease: amyloid beta and tau. The amyloid and tau lowering functions of this gene were demonstrated in both human and mouse cells. Amyloid beta is responsible for the plaques found in...

2009-11-11 17:52:19

A new study reveals that a previously undiscovered mouse gene reduces the two major pathological perturbations commonly associated with Alzheimer's disease (AD). The research, published by Cell Press in the November 12 issue of the journal Neuron, finds that the novel gene interacts with a key cellular enzyme previously linked with AD pathology, thereby uncovering a new strategy for treating this devastating disorder. AD is an incurable neurodegenerative disease characterized by a...

2009-09-30 10:55:31

Laboratory study shows drug targets chaperone Hsp70 to reduce Alzheimer's protein Inhibiting the protein Hsp70 rapidly reduces brain levels of tau, a protein associated with Alzheimer's disease when it builds up abnormally inside nerve cells affecting memory, neuroscientists at the University of South Florida found. The study is reported online Sept. 29 in the Journal of Neuroscience. "Now that we've discovered that targeting the chaperone protein Hsp70 can clear tau, it could be helpful in...

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2009-06-08 11:15:00

New research has shown that a rogue protein thought to cause Alzheimer's can spread through the brain, turning healthy tissue bad, BBC News reported.The tau protein may share characteristics with the prion proteins that cause vCJD. Scientists found it triggered formation of protein tangles linked to Alzheimer's after they injected it into the brains of healthy mice.But the study, published in the Nature Cell Biology, said this did not mean tau could be passed from person to person.Tau is a...


Word of the Day
tessitura
  • The prevailing range of a vocal or instrumental part, within which most of the tones lie.
This word is Italian in origin and comes from the Latin 'textura,' web, structure.