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Last updated on April 23, 2014 at 10:57 EDT

Latest Taxus brevifolia Stories

2010-09-30 20:20:46

MIT researchers and collaborators from Tufts University have now engineered E. coli bacteria to produce large quantities of a critical compound that is a precursor to the cancer drug Taxol, originally isolated from the bark of the Pacific yew tree. The tree's bacteria can produce 1,000 times more of the precursor, known as taxadiene, than any other engineered microbial strain. The technique, described in the Oct. 1 issue of Science, could bring down the manufacturing costs of Taxol and also...

2009-04-03 11:38:10

Research by Michigan State University chemist Kevin Walker is paving the way for potentially cleaner, more efficient production of cancer-fighting paclitaxel "“ better known as the blockbuster drug Taxol. First isolated from the bark of the Pacific yew in 1967, paclitaxel has since been made by synthetically modifying an intermediate substance isolated from yew needles using toxic solvents or by fermenting cell cultures. Walker's method employs natural enzymes instead....