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Latest TB Stories

2011-12-29 09:40:35

A UT Southwestern Medical Center study using a sophisticated “glass mouse” research model has found that multidrug-resistant tuberculosis (TB) is more likely caused in patients by speedy drug metabolism rather than inconsistent doses, as is widely believed. If the study published in The Journal of Infectious Diseases is borne out in future investigations, it may lead to better ways to treat one of the world´s major infectious diseases. Health workers worldwide currently...

2011-12-10 01:17:10

In populations with a low prevalence of tuberculosis (TB), the majority of positives with the three tests commercially available in the U.S for the diagnosis of TB are false positives, according to a new study. "We compared commercially available tests for latent tuberculosis infection (LTBI) in a diverse population with a low LTBI prevalence," said James Mancuso, MD, DrPH, of the Walter Reed Army Institute of Research Preventive Medicine Residency Program. "Our results suggest that in...

2011-12-10 01:15:55

The incidence of tuberculosis (TB) diagnosis is significantly increased in mothers postpartum, suggesting a potential new population to target for screening, according to a new UK-wide cohort study. In the joint study between the Health Protection Agency and the University of East Anglia, researchers analyzed data on all women with pregnancies between 1996 and 2008 from the General Practice Research Database, which contains records from 460 practices across the UK, representing 5.5 percent...

2011-12-02 01:18:38

Researchers have discovered that over a million people worldwide diagnosed with TB go on to develop an incurable but manageable fungal infection which is usually left untreated because it is mistaken for a recurrence of the disease. In a new report published today in the Bulletin of the World Health Organization, the researchers from University of Manchester and University of Toronto say because the X-ray features and symptoms are so similar doctors often misdiagnose and prescribe the...

2011-12-01 14:29:16

One-third of the world's people have latent TB Statens Serum Institut and Aeras today announced the initiation of the first Phase I clinical trial of a new candidate TB vaccine designed to protect people latently infected with TB from developing active TB disease. The trial is being conducted by the South African Tuberculosis Vaccine Initiative (SATVI) at its field site in Worcester, in the Western Cape province of South Africa. Dr. Hassan Mahomed is the principal investigator. "Two...

2011-11-30 14:53:11

A University of Adelaide scientist says much more could be done to predict the likelihood and spread of serious disease - such as tuberculosis (TB) or foot-and-mouth disease - in Australian wildlife and commercial stock. Professor Corey Bradshaw and colleagues have evaluated freely available software tools that provide a realistic prediction of the spread of disease among animals. They used a combination of models to look at the possible spread of TB among feral water buffalo in the...

2011-11-30 10:56:57

In this week's PLoS Medicine, Christian Lienhardt from the WHO in Geneva, Switzerland and colleagues announce that the Stop TB Partnership and the WHO Stop TB Department have launched the TB Research Movement. In the article the authors describe the development of the Research Movement strategic plan, highlighting progress in its two key components: (1) the analysis of the global funding landscape for TB research, and (2) the development of a global TB research agenda. The problem...

2011-11-30 10:50:15

In research at SRI International, scientists evaluating new drug targets against tuberculosis (TB) recently validated the preclinical effectiveness of a target that could rapidly eliminate infections and potentially shorten treatment time. The new drug target is a protein called DNA gyrase B, found in bacteria that cause TB infections. DNA gyrase is an enzyme consisting of two subunits: gyrase A and gyrase B. Although gyrase A is often the target of antibiotics, such as ciprofloxacin,...


Word of the Day
mundungus
  • A stinking tobacco.
  • Offal; waste animal product; organic matter unfit for consumption.
This word comes from the Spanish 'mondongo,' tripe, entrails.