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Latest TB Stories

2011-12-02 01:18:38

Researchers have discovered that over a million people worldwide diagnosed with TB go on to develop an incurable but manageable fungal infection which is usually left untreated because it is mistaken for a recurrence of the disease. In a new report published today in the Bulletin of the World Health Organization, the researchers from University of Manchester and University of Toronto say because the X-ray features and symptoms are so similar doctors often misdiagnose and prescribe the...

2011-12-01 14:29:16

One-third of the world's people have latent TB Statens Serum Institut and Aeras today announced the initiation of the first Phase I clinical trial of a new candidate TB vaccine designed to protect people latently infected with TB from developing active TB disease. The trial is being conducted by the South African Tuberculosis Vaccine Initiative (SATVI) at its field site in Worcester, in the Western Cape province of South Africa. Dr. Hassan Mahomed is the principal investigator. "Two...

2011-11-30 14:53:11

A University of Adelaide scientist says much more could be done to predict the likelihood and spread of serious disease - such as tuberculosis (TB) or foot-and-mouth disease - in Australian wildlife and commercial stock. Professor Corey Bradshaw and colleagues have evaluated freely available software tools that provide a realistic prediction of the spread of disease among animals. They used a combination of models to look at the possible spread of TB among feral water buffalo in the...

2011-11-30 10:56:57

In this week's PLoS Medicine, Christian Lienhardt from the WHO in Geneva, Switzerland and colleagues announce that the Stop TB Partnership and the WHO Stop TB Department have launched the TB Research Movement. In the article the authors describe the development of the Research Movement strategic plan, highlighting progress in its two key components: (1) the analysis of the global funding landscape for TB research, and (2) the development of a global TB research agenda. The problem...

2011-11-30 10:50:15

In research at SRI International, scientists evaluating new drug targets against tuberculosis (TB) recently validated the preclinical effectiveness of a target that could rapidly eliminate infections and potentially shorten treatment time. The new drug target is a protein called DNA gyrase B, found in bacteria that cause TB infections. DNA gyrase is an enzyme consisting of two subunits: gyrase A and gyrase B. Although gyrase A is often the target of antibiotics, such as ciprofloxacin,...

2011-11-14 23:39:49

The stealth art of infectious agents: Researchers uncover why the body can't defend against tuberculosis Tuberculosis, which kills over 2 million people each year, is caused primarily by infectious bacteria known as Mycobacterium tuberculosis — or Mtb. Mtb targets human immune cells as part of its strategy to avoid detection, effectively neutralizing the body's immune response. Up until now, scientists had a general understanding of the process, but researchers in the Immunity and...

2011-11-09 10:01:09

A study led by Frank Cobelens of the Amsterdam Institute of Global Health and Development, Amsterdam, The Netherlands and colleagues reports on the cost-effectiveness of implementing the Xpert MTB/RIF diagnostic test for tuberculosis (TB) in high burden countries. Based on their findings, which are published in this week's PLoS Medicine, the authors predict that Xpert will be a cost-effective method of TB diagnosis, compared with current standard techniques, in low- and middle-income...


Word of the Day
endocarp
  • The hard inner (usually woody) layer of the pericarp of some fruits (as peaches or plums or cherries or olives) that contains the seed.
This word comes from the Greek 'endon,' in, within, plus the Greek 'karpos', fruit.
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